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Authors: Robert D. Sanders, M.B.B.S., Ph.D., F.R.C.A. et al Anesthesiology published on December 15, 2016. Background: The isolated forearm technique allows assessment of consciousness of the external world (connected consciousness) through a verbal command to move the hand (of a tourniquet-isolated arm) during intended general anesthesia. Previous isolated forearm technique data suggest that the incidence of […]
Read MoreAuthors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology published on December 15, 2016. Background: Although peripheral nerve blocks decrease pain after total knee arthroplasty, the population-level impact of nerve blocks on arthroplasty resource utilization is unknown. Methods: We conducted a population-based cohort study using linked administrative data from Ontario, Canada. We identified all adults having […]
Read MoreAggregatibacter actinomycetemcomitans may trigger inflammation in both patients with periodontal disease and rheumatoid arthritis. By Nikki Kean A bacteria that causes gum disease may also hold the key to triggering rheumatoid arthritis (RA). In a new report, investigators at Johns Hopkins say the common denominator in periodontal disease and in many people with RA is Aggregatibacter actinomycetemcomitans.1 An infection […]
Read MoreEdited by Susan Sadoughi, MD, and André Sofair, MD, MPH The mortality rate from synthetic opioids besides methadone increased 72% between 2014 and 2015 in the U.S., while heroin-related deaths rose 21%, according to an article in MMWR. Using data from the National Vital Statistics System, researchers found that synthetic opioid (e.g., fentanyl) deaths increased from 1.8 to […]
Read MoreInterview with Abby R. Rosenberg, MD, MS By Thomas G. Ciccone Matters concerning negative prognosis, transitioning into hospice care, end-of-life (EoL) scenarios, and other related topics can be very hard to discuss with patients and their family members. Having to conduct these sensitive conversations with pediatric patients presents even more challenges, considering certain ethical and emotional […]
Read MoreBy Daniel M. Lindberg, MD Dr. Lindberg is an associate editor with NEJM Journal Watch Emergency Medicine, from which this story was adapted. Evidence that sweet solutions improve pain for neonates during painful procedures has been compelling for more than a decade, according to a meta-analysis in Pediatrics. Using a robust search strategy, researchers identified 168 randomized, […]
Read MoreEdited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Regular, long-term use of acetaminophen and nonsteroidal anti-inflammatory drugs is associated with modestly elevated risk for hearing loss in women, suggests an American Journal of Epidemiology study. Over 55,000 women aged 44–69 in the Nurses’ Health Study answered questions about incident hearing loss and how often they […]
Read MoreAuthors: Alejandra MD, PhD et al Objective: We report the results of a pilot, enrichment-design, placebo-controlled crossover trial of pregabalin for the treatment of prediabetic small-fiber neuropathic pain. Methods: Individuals with impaired fasting glucose or impaired glucose tolerance and neuropathic pain were evaluated according to UTAH Early Neuropathy Scale (UENS), Quantitative Sensory Testing, and intraepidermal […]
Read MoreWith mainstream attention focused on the opioid overdose epidemic in the US, prices for naloxone are rising substantially, leading doctors to call for legislative support to stop unjustified naloxone price increases. By Thomas G. Ciccone Interview with Ravi Gupta, BS, and commentary from Jeffrey Gudin, MD, and Jeff Fudin, PharmD As opioid overdose deaths continue to […]
Read MoreAuthors: Pavel S. Roshanov, M.D., M.Sc. et al Anesthesiology 1 2017, Vol.126, 16-27. Background: The effect on cardiovascular outcomes of withholding angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac surgery is unknown. Methods: In this international prospective cohort study, the authors analyzed data from 14,687 patients (including 4,802 angiotensin-converting enzyme inhibitor/angiotensin II […]
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