Authors: Goodnough, Lawrence T. MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 282–289 Abstract Sporadic Zika virus infections had only occurred in Africa and Asia until an outbreak in Micronesia (Oceania) in 2007. In 2013 to 2014, several outer Pacific Islands reported local outbreaks. Soon thereafter, the […]
Read MoreAuthors: Whiles BB et al., Crit Care Med 2017 Feb 6; In this study, earlier administration was associated with decreased progression to septic shock. Early antibiotics are associated with decreased mortality for patients with severe sepsis. To evaluate whether early administration of antibiotics is also associated with decreased progression to septic shock, investigators conducted a retrospective cohort […]
Read MoreAuthors: Drewry AM et al., Crit Care Med 2017 Feb 17; A meta-analysis showed that antipyretic therapy did not reduce 28-day mortality. Fever is certainly a sign of infection. But does treatment of fever improve outcomes in patients with sepsis? To find out, investigators conducted a meta-analysis of eight randomized trials (1507 patients) and six observational studies […]
Read MoreAuthors: Adam W. Amundson, M.D. et al Anesthesiology published on March 2, 2017. Background: Multimodal analgesia is standard practice for total knee arthroplasty; however, the role of regional techniques in improved perioperative outcomes remains unknown. The authors hypothesized that peripheral nerve blockade would result in lower pain scores and opioid consumption than two competing periarticular […]
Read MoreEdited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Migraine is associated with risk for stroke caused by cervical artery dissection, according to a JAMA Neurology study. Using a large Italian stroke registry, researchers studied nearly 2500 adults aged 18 to 45 who experienced a first ischemic stroke; 13% had spontaneous cervical […]
Read MoreA review and retrospective study on the effectiveness of scrambler (stimulation) therapy to reduce noncancer-related neuropathic pain syndromes, with apparent, maximal pain relief achieved at 1 to 2 weeks. By Alexandra M. Lesenskyj, Christina R. Maxwell, PhD, MTR and Ricardo A. Cruciani, MD, PhD Minimizing the incidence of medication dependence in patients with chronic neuropathic […]
Read MorePromising data suggests rapid access to physical therapy may improve outcomes for patients with acute back pain, who typically wait much longer to receive evaluation from a physician. By Thomas G. Ciccone Interview with Michael Campian, DO, and Pamela Hansen, MD Improving care for patients with low back pain could be as simple as providing […]
Read MoreThe authors discuss a special set of neurohormones with pain-related functions, which if tapped for their intrinsic use, may diminish the need for opioids. By John Claude Krusz, PhD, MD and Forest Tennant, MD, DrPH The recent discovery and awareness that the central nervous system (CNS) makes specific hormones for intrinsic use in addition to […]
Read MoreChronic pain and depression often go hand in hand. The prevalence of pain symptoms in patients with depression ranges from 15% to 100% while the prevalence for concurrent major depression in patients identified as having pain ranged from 5% to 85%. Authors: David Cosio, PhD et al We are introducing a monthly column on mental health disorders […]
Read MoreAuthors: Emine Ozgur Bayman, Ph.D. et al Anesthesiology published on March 2, 2017. Background: The goal of this study was to detect the predictors of chronic pain at 6 months after thoracic surgery from a comprehensive evaluation of demographic, psychosocial, and surgical factors. Methods: Thoracic surgery patients were enrolled 1 week before surgery and followed […]
Read More