Author: Dr Clemens

Uncategorized Published - 28 March, 2017    By - Dr Clemens
Presepsin (sCD14-ST) Is a Novel Marker for Risk Stratification in Cardiac Surgery Patients

Authors: Hagen Bomberg, M.D. et al Anesthesiology 4 2017, Vol.126, 631-642. Background: Presepsin (soluble cluster-of-differentiation 14 subtype [sCD14-ST]) is a humoral risk stratification marker for systemic inflammatory response syndrome and sepsis. It remains unknown whether presepsin can be used to stratify risk in elective cardiac surgery. The authors therefore determined the usefulness of presepsin for risk […]

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Uncategorized Published - 28 March, 2017    By - Dr Clemens
Validation and Calibration of the Risk Stratification Index

Authors: George F. Chamoun et al Anesthesiology 4 2017, Vol.126, 623-630. Background: The Risk Stratification Index was developed from 35 million Medicare hospitalizations from 2001 to 2006 but has yet to be externally validated on an independent large national data set, nor has it been calibrated. Finally, the Medicare Analysis and Provider Review file now allows […]

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Uncategorized Published - 28 March, 2017    By - Dr Clemens
Adding Examples to the ASA-Physical Status Classification Improves Correct Assignment to Patients

Authors: Erin E. Hurwitz, M.D. et al Anesthesiology 4 2017, Vol.126, 614-622. Background: Despite its widespread use, the American Society of Anesthesiologists (ASA)-Physical Status Classification System has been shown to result in inconsistent assignments among anesthesiologists. The ASA-Physical Status Classification System is also used by nonanesthesia-trained clinicians and others. In 2014, the ASA developed and approved examples […]

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Uncategorized Published - 27 March, 2017    By - Dr Clemens
Association of the Hospital Volume of Frail Surgical Patients Cared for with Outcomes after Elective, Major Noncardiac Surgery: A Retrospective Population-based Cohort Study

Authors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology 4 2017, Vol.126, 602-613. Background: Frailty is a risk factor for adverse postoperative outcomes. Hospitals that perform higher volumes of surgery have better outcomes than low-volume providers. We hypothesized that frail patients undergoing elective surgery at hospitals that cared for a higher volume of similarly frail patients […]

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Uncategorized Published - 27 March, 2017    By - Dr Clemens
Paradoxical Emergence: Administration of Subanesthetic Ketamine during Isoflurane Anesthesia Induces Burst Suppression but Accelerates Recovery

Authors: Viviane S. Hambrecht-Wiedbusch, Ph.D. et al Anesthesiology 3 2017, Vol.126, 482-494. Background: Promoting arousal by manipulating certain brain regions and/or neurotransmitters has been a recent research focus, with the goal of trying to improve recovery from general anesthesia. The current study tested the hypothesis that a single subanesthetic dose of ketamine during isoflurane anesthesia would increase […]

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Uncategorized Published - 27 March, 2017    By - Dr Clemens
Influence of Ethanol on Oxycodone-induced Respiratory Depression: A Dose-escalating Study in Young and Elderly Individuals

Authors: Rutger van der Schrier, M.D. et al Anesthesiology 3 2017, Vol.126, 534-542. Background: Respiratory depression is a potentially fatal complication of opioid use, which may be exacerbated by simultaneous ethanol intake. In this three-way sequential crossover dose-escalating study, the influence of coadministration of oral oxycodone and intravenous ethanol was assessed on resting ventilation, apneic events and […]

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Uncategorized Published - 27 March, 2017    By - Dr Clemens
ACP Recommendations for Noninvasive Therapies for Acute, Subacute, and Chronic Low Back Pain

Authors: Atlas SJ., Ann Intern Med 2017 Feb 14; The American College of Physicians has evaluated a broad array of treatment options. Sponsoring Organization: American College of Physicians (ACP) Target Audience: All clinicians Target Population: Adults with acute (<4 weeks), subacute (4–12 weeks), or chronic (>12 weeks) back pain in primary care settings Background The ACP has developed a […]

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Uncategorized Published - 27 March, 2017    By - Dr Clemens
Indiana Approves New Anesthesiologist Assistant Program

On February 9, the Indiana Commission for Higher Education (ICHE) approved a new Master of Science in Anesthesia (MSA) degree. The graduate level program will be offered through the Indiana University School of Medicine in Indianapolis. Accreditation is in process. Further information about the MSA degree and program can be found at http://anesthesia.iu.edu/Education/AnesthesiologistAssistant/Introduction.aspx. With the ICHE’s […]

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Uncategorized Published - 24 March, 2017    By - Dr Clemens
Intra-op Beta Blockers Lower Post-op Opioid Use, Nausea and Length of Stay

Although typically used to promote hemodynamic stability, beta blockers may have another purpose, according to a team of Montreal researchers: reducing postoperative pain. Their systematic review concluded that continuous beta-blocker infusions during surgery can decrease postoperative opioid consumption, the incidence of nausea and PACU length of stay, all with few side effects. “We know that […]

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Uncategorized Published - 24 March, 2017    By - Dr Clemens
Optimize Patient Before Intubation to Reduce ICU Complications

Oxygenation and hemodynamic stabilization before intubation could help reduce complications for patients in the ICU, according to a recent study. Procedurally related complications from airway management occurred commonly in the ICU, despite first-attempt success, researchers found. “We’re trying to address the risk factors for these complications prior to intubation,” said Thomas Navarro, MD, of the […]

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