Authors: Thomas Mistral, M.D. et al Anesthesiology published on March 30, 2017. Background: The purpose of this study was to test the diagnostic performance of clinical judgment for the prediction of a significant injury with whole-body computed tomography scanning after high-energy trauma. Methods: The authors conducted an observational prospective study in a single level-I trauma center. Adult patients […]
Read MoreAuthor(s) Michael Long1,2*, Melissa Machan2,3, Luis Tollinche1 Affiliation(s) 1Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, USA. 2Barry University, College of Health Sciences, Hollywood, USA. 3Department of Anesthesiology, Plantation General Hospital, Plantation, USA. ABSTRACT Study Objective: Establish complications and risk factors that are associated with blind tube insertion, evaluate the validity of […]
Read MoreEdited by Susan Sadoughi, MD, and André Sofair, MD, MPH Duloxetine, venlafaxine, pregabalin, oxcarbazepine, tricyclic antidepressants, atypical opioids (e.g., tapentadol), and botulinum toxin are all more effective than placebo in reducing pain associated with diabetic peripheral neuropathy, according to a Neurology review. Researchers examined 50 new trials of various diabetic peripheral neuropathy medications, along with 50 studies that were […]
Read MoreAuthor: Fran Lowry Prescribing benzodiazepines pro re nata (PRN), or on an “as-needed” basis, may lead to misuse, new research shows. Clinicians may erroneously assume that instructing a patient to take the medication as needed will decrease the likelihood that they will take that medication, but it may be having the opposite effect, investigators found. […]
Read MoreAUTHORS: Kirsch, Muriëlle MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 588–598 BACKGROUND: To reduce head movement during resting state functional magnetic resonance imaging, post-coma patients with disorders of consciousness (DOC) are frequently sedated with propofol. However, little is known about the effects of this sedation on the […]
Read MoreAUTHORS: Neice, Andrew E. MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 915–921 BACKGROUND: Pupillary unrest under ambient light (PUAL) is the fluctuation in pupil diameter in time around a mean value. PUAL is augmented by light and diminished by administration of opioids. We hypothesized that, because pupillary […]
Read MoreAUTHORS: Abdelaal Ahmed Mahmoud et al Anesthesia & Analgesia: December 8, 2016 BACKGROUND: Antegrade cannulation of peripheral veins is the usual practice. Blood stasis between a catheter and the wall of the vein or at its tip in addition to catheter-induced phlebitis may initiate a thrombosis. The use of retrograde ventriculojugular shunts against the direction of […]
Read MoreAUTHORS: Guay J et al Anesthesia & Analgesia 123 (6), 1591-1602 (Dec 2016) BACKGROUND The aim of this review was to compare the effects of postoperative epidural analgesia with local anesthetics to postoperative systemic or epidural opioids in terms of return of gastrointestinal transit, postoperative pain control, postoperative vomiting, incidence of gastrointestinal anastomotic leak, hospital […]
Read MoreAUTHORS: Sauer, Reine-Solange PhD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 675–685 BACKGROUND: Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their clinical use. Cyclodextrins […]
Read MoreSeronegative rheumatoid arthritis (RA) is strongly associated with fibromyalgia, according to a newly published study. However, one expert suggests the difference seen between seronegative vs seropositive RA and fibromyalgia might reflect the greater scrutiny of patients with seronegative RA in typical clinical practice. Jayanth Doss, MD, from the Division of Rheumatology and Immunology, Duke University, […]
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