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For patients with acute traumatic brain injury (TBI), the higher the prehospital systolic blood pressure the better — a finding that challenges the conventional wisdom that there is a clinically meaningful threshold, new research suggests. The study — the largest to date to look at this issue — found a linear association between lowest prehospital […]
Read MoreAUTHORS: Zaouter, Cédrick MD et al Anesthesia & Analgesia: December 2016 BACKGROUND: Recently, several trials have shown that closed-loop sedation is feasible. No study has used automated sedation in extremely frail patients, such as those scheduled for transcatheter aortic valve implantation (TAVI). We developed and tested a novel automated sedation system for this kind of population […]
Read MoreAUTHORS: Guay J et al Anesthesia & Analgesia 123 (6), 1591-1602 (Dec 2016) BACKGROUND The aim of this review was to compare the effects of postoperative epidural analgesia with local anesthetics to postoperative systemic or epidural opioids in terms of return of gastrointestinal transit, postoperative pain control, postoperative vomiting, incidence of gastrointestinal anastomotic leak, hospital […]
Read MoreThe number of people dying from an opioid overdose rose nearly 16% from 2014 to 2015, but the increase had little to do — at least directly — with prescription painkillers such as oxycodone or hydrocodone, the Centers for Disease Control and Prevention (CDC) reported last week. Instead, the chief culprits behind the spike were […]
Read MoreAuthors: Eunsu Kang et al BMC Anesthesiol. 2016;16(116) Background: Dexmedetomidine, a selective alpha-2 agonist, has sedative, analgesic, and anxiolytic effects without respiratory depression. Dexmedetomidine can cause a biphasic cardiovascular response, and induce transient hypertension. Hypotension is a common complication of spinal anesthesia. Decreasing anxiety of patients before procedure is important for high quality of procedure. This study […]
Read MoreAUTHORS: Tawfik, Mohamed Mohamed MD et al Anesthesia & Analgesia: April 2017 – Volume 124 – Issue 4 – p 1291–1297 BACKGROUND: Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral […]
Read MoreAuthor: Jaber S et al. JAMA 2016 Mar 15. Hernández G et al. JAMA 2016 Mar 15.Spoletini G et al. JAMA 2016 Mar 15. High-flow oxygen and noninvasive positive pressure ventilation lowered reintubation rates in selected patient populations. During the past few years, interest has grown in using high-flow oxygen (HFO) and noninvasive positive pressure ventilation (NPPV) in lieu of intubation and […]
Read MoreAuthors: Panwar R et al. Am J Respir Crit Care Med 2016 Jan 1. Targeting to 88%–92% did not cause harm. The optimal oxygenation goal for patients who are receiving invasive mechanical ventilation remains unclear. Clinicians usually target resolution of hypoxemia and pay little attention to weaning levels of oxygen once 100% saturation has been achieved. However, harms […]
Read MoreAUTHORS: Richardson, Michael G. MD et Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 548–553 BACKGROUND: Evidence on the analgesic effectiveness of nitrous oxide for labor pain is limited. Even fewer studies have looked at patient satisfaction. Although nitrous oxide appears less effective than neuraxial analgesia, it is unclear whether labor […]
Read MoreAUTHORS: Vanda G. MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 438–444 BACKGROUND: Haloperidol is an antipsychotic. At low doses, it is a useful agent for the prophylaxis of postoperative nausea and vomiting (PONV). However, its use for treating established PONV has not been well studied. METHODS: This […]
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