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Authors: Didier Roulin, MD et al Annals of Surgery. 2016;264(5):717-722. Are the 72 Hours Still the Rule?: A Randomized Trial Objective: The aim of this study was to compare clinical outcomes of early versus delayed laparoscopic cholecystectomy (LC) in acute cholecystitis with more than 72 hours of symptoms. Background: LC is the treatment of acute cholecystitis, with consensus […]
Read MoreAUTHORS: Eichler, Klaus MD, MPH et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 925–933 BACKGROUND: Pharmacologic pre- and postconditioning with sevoflurane compared with total IV anesthesia in patients undergoing liver surgery reduced complication rates as shown in 2 recent randomized controlled trials. However, the potential health economic consequences of […]
Read MoreAuthors: Sondekoppam, Rakesh V. MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 645–660 The onset of neurologic complications after regional anesthesia is a complex process and may result from an interaction of host, agent, and environmental risk factors. The purpose of this systematic review was examine the qualitative […]
Read MoreHis deputy, Rear Adm. Sylvia Trent Adams, will replace him on an interim basis. Over the weekend, Surgeon General Vivek Murthy was asked by the Trump administration to resign from his post, and then was replaced by his deputy, Rear Adm. Sylvia Trent Adams, a nurse. Murthy’s dismissal came roughly halfway through his four-year term, […]
Read MoreThe FDA has approved label changes for the use of general anesthesia and sedation drugs in young children, given warnings issued in late 2016 about the potential adverse effects on brain development with lengthy or repeated use. The label changes are as follows: A new warning states that exposure for prolonged periods or during multiple […]
Read MoreThe FDA has approved abaloparatide (marketed as Tymlos) for the treatment of postmenopausal women with osteoporosis who are at high risk for fracture — that is, those who have had a prior osteoporotic fracture, have multiple fracture risk factors, or have failed or cannot tolerate other osteoporosis therapies. The osteoanabolic agent is a synthetic analog […]
Read MoreEdited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Spinal manipulation improves pain and function in adults with acute low back pain, although the effects are “clinically modest,” according to the authors of a JAMA meta-analysis. The analysis included 26 randomized controlled trials comparing spinal manipulation with sham or alternative treatments (e.g., physical therapy) […]
Read MoreAuthors: Abdullah Sulieman Terkawi, M.D. et al Anesthesiology 5 2017, Vol.126, 923-937 Background: Optimal analgesia for total knee arthroplasty remains challenging. Many modalities have been used, including peripheral nerve block, periarticular infiltration, and epidural analgesia. However, the relative efficacy of various modalities remains unknown. The authors aimed to quantify and rank order the efficacy of available analgesic […]
Read MoreAuthors: Alexander Zarbock, M.D. et Anesthesiology 5 2017, Vol.126, 787-798. Background: In a multicenter, randomized trial, the authors enrolled patients at high-risk for acute kidney injury as identified by a Cleveland Clinic Foundation score of 6 or more. The authors enrolled 240 patients at four hospitals and randomized them to remote ischemic preconditioning or control. The authors […]
Read MoreAuthor: David H. Chestnut, M.D. Anesthesiology 5 2017, Vol.126, 780-786 Many observers have concluded that we have a crisis of professionalism in the practice of medicine. In this essay, the author identifies and discusses personal attributes and commitments important in the development and maintenance of physician professionalism: humility, servant leadership, self-awareness, kindness, altruism, attention to personal […]
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