Author: Dr Clemens

Uncategorized Published - 11 August, 2017    By - Dr Clemens
Nocturnal Dexmedetomidine in Nonintubated, Critically Ill Patients: Sleep or Sedation?

Authors: Haley Goucher Miranda, M.D. et al Anesthesiology 8 2017, Vol.127, 397-398. To the Editor: In November 2016’s issue of Anesthesiology, Wu et al., in their article “Low-dose Dexmedetomidine Improves Sleep Quality Pattern in Elderly Patients after Noncardiac Surgery in the Intensive Care Unit: A Pilot Randomized Controlled Trial,”1  demonstrated polysomnographic improvement in sleep in patients treated with […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Predicting Perioperative Transfusion in Elective Hip and Knee Arthroplasty: A Validated Predictive Model

Authors: Josephine To, B.Pharm. et al Anesthesiology 8 2017, Vol.127, 317-325. Background: Preoperative anemia is a significant predictor of perioperative erythrocyte transfusion in elective arthroplasty patients. However, interactions with other patient and procedure characteristics predicting transfusion requirements have not been well studied. Methods: Patients undergoing elective primary total hip arthroplasty or total knee arthroplasty at a tertiary hospital […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Blind Intubation through Self-pressurized, Disposable Supraglottic Airway Laryngeal Intubation Masks: An International, Multicenter, Prospective Cohort Study

Authors: Kurt Ruetzler, M.D. et al Anesthesiology 8 2017, Vol.127, 307-316 Background: Supraglottic airway devices commonly are used for securing the airway during general anesthesia. Occasionally, intubation with an endotracheal tube through a supraglottic airway is indicated. Reported success rates for blind intubation range from 15 to 97%. The authors thus investigated as their primary outcome the […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Left Lateral Table Tilt for Elective Cesarean Delivery under Spinal Anesthesia Has No Effect on Neonatal Acid–Base Status: A Randomized Controlled Trial

Authors: Allison J. Lee, M.D. et al Anesthesiology 8 2017, Vol.127, 241-249. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
A Prospective Study of Age-dependent Changes in Propofol-induced Electroencephalogram Oscillations in Children

Authors: Johanna M. Lee, A.B. et al Anesthesiology 8 2017, Vol.127, 293-306. Background: In adults, frontal electroencephalogram patterns observed during propofol-induced unconsciousness consist of slow oscillations (0.1 to 1 Hz) and coherent alpha oscillations (8 to 13 Hz). Given that the nervous system undergoes significant changes during development, anesthesia-induced electroencephalogram oscillations in children may differ from those […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Pupillometry-guided Intraoperative Remifentanil Administration versus Standard Practice Influences Opioid Use: A Randomized Study

Authors: Nada Sabourdin, M.D. et al Anesthesiology 8 2017, Vol.127, 284-292. Background: Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits in clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact of intraoperative pupillometry monitoring on perioperative opioid consumption in major gynecologic surgery. Methods: After […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Validation of Innovative Techniques for Monitoring Nociception during General Anesthesia: A Clinical Study Using Tetanic and Intracutaneous Electrical Stimulation

Authors: Sandra Funcke, M.D. et al Anesthesiology 8 2017, Vol.127, 272-283. Background: This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth Index (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, and bispectral index, with regard to diagnostic accuracy and prediction probability for nociceptive response. The primary endpoint was the correlation […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort

Authors: Danqing Hu, M.D. et al Anesthesiology 8 2017, Vol.127, 227-240. Background: Exposure of young animals to general anesthesia causes neurodegeneration and lasting behavioral abnormalities; whether these findings translate to children remains unclear. This study used a population-based birth cohort to test the hypothesis that multiple, but not single, exposures to procedures requiring general anesthesia before age […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Decision to Extubate Brain-injured Patients: Limiting Uncertainty in Neurocritical Care

Authors: Thomas Godet, M.D., Ph.D. et al Anesthesiology 8 2017, Vol.127, 217-219. WHATEVER the field of critical care medicine, timely decision to extubate, to both prevent complications associated with extubation failure and undue ventilatory support, remains challenging. Finding reliable clinical predictors of extubation success still appears as a holy grail.1  In this issue of Anesthesiology, Asehnoune et al. […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Phenylephrine Infusion: Driving a Wedge in Our Practice of Left Uterine Displacement?

AUTHORS: Michaela K. Farber, M.D. et al Anesthesiology 8 2017, Vol.127, 212-214. “It is clearly important to critically evaluate aspects of our practice that may be perpetuated based on tradition more than a firm evidence base.” THE avoidance of maternal hypotension during spinal anesthesia for cesarean delivery is of paramount importance to maintain placental blood flow […]

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