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Authors: Brad S. Karon, M.D., Ph.D. et al Anesthesiology 9 2017, Vol.127, 466-474. Background: The aim of this study was to evaluate the use of a glucose meter with surgical patients under general anesthesia in the operating room. Methods: Glucose measurements were performed intraoperatively on 368 paired capillary and arterial whole blood samples using a Nova StatStrip (Nova […]
Read MoreAuthors: László Asztalos, M.D. et al Anesthesiology 9 2017, Vol.127, 441-449. Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block. Methods: Sixty-five patients were randomly assigned, and 64 were […]
Read MoreAuthors: Karim Asehnoune, M.D., Ph.D. et al Anesthesiology 8 2017, Vol.127, 338-346. Background: Patients with brain injury are at high risk of extubation failure. Methods: We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in patients […]
Read MoreAuthors: Sandra Funcke, M.D. et al Anesthesiology 8 2017, Vol.127, 272-283. Background: This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth Index (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, and bispectral index, with regard to diagnostic accuracy and prediction probability for nociceptive response. The primary endpoint was the correlation […]
Read MoreAuthors: Maged Y. Argalious, M.D., M.Sc., M.B.A., M.Ed., F.A.S.E. et Anesthesiology 9 2017, Vol.127, 457-465. Background: Whether patients on testosterone replacement therapy undergoing noncardiac surgery have an increased risk of postoperative in-hospital mortality and cardiovascular events remains unknown. We therefore sought to identify the impact of testosterone replacement on the incidence of a composite of postoperative in-hospital […]
Read MoreAuthors: Matthieu Biais, M.D., Ph.D. et al Anesthesiology 9 2017, Vol.127, 450-456 Background: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of 250 ml crystalloid in mechanically […]
Read MoreAuthors: Allison J. Lee, M.D. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining baseline systolic blood pressure, there would […]
Read MoreEdited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Concurrent prescription of psychotropic medications and opioids in pregnant women may put their infants at increased risk for neonatal drug withdrawal, according to a study in The BMJ. Using Medicaid data, researchers studied over 200,000 women who were prescribed opioids in the last 45 days of […]
Read MoreAuthors: Stephens RJ et al., Chest 2017 Jun 29; In a prospective study of mechanically ventilated emergency department patients, deeper sedation levels were associated with increased mortality. Deeper sedation levels within the first 48 hours of intensive care unit admission have been associated with longer duration of mechanical ventilation and increased mortality. Unclear, however, is whether deeper […]
Read MoreAuthors: Jacqueline M. Leung, M.D., M.P.H. et al Anesthesiology published on July 20, 2017 Background: Postoperative pain and opioid use are associated with postoperative delirium. We designed a single-center, randomized, placebo-controlled, parallel-arm, double-blinded trial to determine whether perioperative administration of gabapentin reduced postoperative delirium after noncardiac surgery. Methods: Patients were randomly assigned to receive placebo (N = 347) […]
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