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AUTHORS: Abirami Kumaresan, M.D. Anesthesiology 6 2018, Vol.128, 1187-1192. doi:10.1097/ALN.0000000000002159 Background: The effects of prone positioning on esophageal pressures have not been investigated in mechanically ventilated patients. Our objective was to characterize effects of prone positioning on esophageal pressures, transpulmonary pressure, and lung volume, thereby assessing the potential utility of esophageal pressure measurements in setting positive end-expiratory […]
Read MoreFluid restriction has no impact on disability-free survival; increases risk of acute kidney injury A restrictive fluid regimen is not associated with increased disability-free survival for patients at increased risk of complications during major abdominal surgery, but is associated with increased acute kidney injury, according to a study published online May 10 in the New England […]
Read MoreLocation of inflammation may determine which patients are successfully treated with steroid injections Authors: Daniel Albrecht, PhD et al Pain May 2018 A study by Massachusetts General Hospital (MGH) investigators has found, for the first time in humans, that patients with chronic sciatica — back pain that shoots down the leg — have evidence of inflammation […]
Read MoreAUTHORS: Kirk Hogan, M.D., J.D. Anesthesiology 6 2018, Vol.128, 1260-1261. The article by Block et al. reports that 94% of teenagers with broadly distributed, decreased white matter integrity and volume on magnetic resonance imaging of their brains inhaled nitrous oxide for over an hour during surgery and anesthesia in their first year of life. A manuscript cited by […]
Read MoreWe would like to thank all of the heroes that make today possible for those of us who live in the greatest nation in the world. All of our readers please enjoy your family and be safe.
Read MoreThe U.S. Food and Drug Administration has approved erenumab (Aimovig™, Amgen and Novartis), a first-in-class calcitonin gene-related peptide (CGRP) antagonist, for the prevention of migraine in adults. Erenumab consistently demonstrated an ability to reduce monthly migraine days in patients with episodic and chronic migraine in 3 major clinical trials, ARISE, STRIVE, and LIBERTY. The drug, which is […]
Read Moreauthors: Evan M. Bloch, M.B., Ch.B., et al N Engl J Med May 2018; 378:1837-1841 The rapid, pandemic spread of Zika virus (ZIKV) spurred an international public health emergency in 2015. Cases of ZIKV infection have now been reported in 85 countries or territories1; in 72 of those locations, no such cases had been […]
Read MoreHarvard Business Review Dec 15, 2017 Authors: Jennifer Perry et al Rising pressure to achieve better medical outcomes with increasingly limited financial resources has created an acute need for more physician leaders. Several studies (including this one) have shown that doctors want to be led by other doctors; they trust physician leaders to make the right […]
Read MoreAUTHORS: Anoop Ramgolam, Ph.D. et al Anesthesiology 6 2018, Vol.128, 1065-1074. Background: Limited evidence suggests that children have a lower incidence of perioperative respiratory adverse events when intravenous propofol is used compared with inhalational sevoflurane for the anesthesia induction. Limiting these events can improve recovery time as well as decreasing surgery waitlists and healthcare costs. This single […]
Read MoreAUTHORS: Gianluca Cappelleri, M.D. et al Anesthesiology published on May 14, 2018. Background: Both extra- and intraneural sciatic injection resulted in significant axonal nerve damage. This study aimed to establish the minimum effective volume of intraneural ropivacaine 1% for complete sensory-motor sciatic nerve block in 90% of patients, and related electrophysiologic variations. Methods: Forty-seven consecutive […]
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