Author: Dr Clemens

Uncategorized Published - 4 January, 2018    By - Dr Clemens
Venovenous Bypass Is Associated With a Lower Incidence of Acute Kidney Injury After Liver Transplantation in Patients With Compromised Pretransplant Renal Function

AUTHORS: Sun, Kai MD et al Anesthesia & Analgesia: November 2017 – Volume 125 – Issue 5 – p 1463–1470 BACKGROUND: Although the hemodynamic benefits of venovenous bypass (VVB) during liver transplantation (LT) are well appreciated, the impact of VVB on posttransplant renal function is uncertain. The aim of this study was to determine if VVB was […]

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Uncategorized Published - 4 January, 2018    By - Dr Clemens
Lack of Association Between the Use of Nerve Blockade and the Risk of Persistent Opioid Use Among Patients Undergoing Shoulder Arthroplasty: Evidence From the Marketscan Database

AUTHORS: Mueller, Kathryn G. et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 1014–1020 BACKGROUND: Persistent opioid use following surgery has received increasing attention from policymakers, researchers, and clinicians. Perioperative nerve blockade has been hypothesized to decrease the risk of persistent opioid use. We examined whether nerve blockade was associated with […]

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Uncategorized Published - 4 January, 2018    By - Dr Clemens
Medication Errors in Pediatric Anesthesia: A Report From the Wake Up Safe Quality Improvement Initiative

AUTHORS: Lobaugh, Lauren M. Y. MD et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 936–942 BACKGROUND: Wake Up Safe is a quality improvement initiative of the Society for Pediatric Anesthesia that contains a deidentified registry of serious adverse events occurring in pediatric anesthesia. The aim of this study was to […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
Overdose Deaths Rose in 2016, While Overall Life Expectancy Fell

The rate of drug overdose deaths in the U.S. rose 21% from 2015 to 2016, reaching 20 per 100,000 population, according to new data from the CDC’s National Center for Health Statistics. Adults aged 25 to 54 had the highest overdose death rates, at roughly 35 per 100,000. Also of note: the overdose death rate […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
Arm Paralysis Reversed Following Nerve Transfer Surgery

Patients with spastic arm paralysis from chronic cerebral injury like a stroke or trauma might benefit from a technique to route a nerve from the nonparalyzed side, suggests a small trial in the New England Journal of Medicine. Chinese researchers randomized 36 males to undergo 12 months of physical therapy either alone or with contralateral C7 […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
Outpatient Total Knee Arthroplasty Is Associated with Higher Risk of Perioperative Complications

Authors: Arshi, Armin MD et al JBJS: December 06, 2017 – Volume 99 – Issue 23 – p 1978–1986 Background: As concerns regarding health-care expenditure in the U.S. remain at the national forefront, outpatient arthroplasty is an appealing option for carefully selected patient populations. The purpose of this study was to determine the nationwide trends and complication […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
End-Expiratory Occlusion Test Predicts Fluid Responsiveness in Patients With Protective Ventilation in the Operating Room

AUTHORS: Biais, Matthieu MD, PhD et al Anesthesia & Analgesia: December 2017 – Volume 125 – Issue 6 – p 1889–1895 BACKGROUND: End-expiratory occlusion test (EEOT) has been proposed to predict fluid responsiveness in mechanically ventilated intensive care unit patients. The utility of this test during low-tidal-volume ventilation remains uncertain. This study aimed to determine whether hemodynamic […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
The 10 signs of ‘BS’ in health care, according to Wharton economists

A special report by University of Pennsylvania health care economists suggests the health care industry suffers from an “acute” problem with “deceptive, misleading, unsubstantiated, and foolish statements”—which they refer to as health care “BS.” Cheat sheet series: Evidence-based practice 101 From Theranos to Watson: BS is everywhere In a special report, Wharton School health care […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin

Authors: Stephen J. Raithel, B.A. et al Anesthesiology published December, 2017. Background: Peripheral nociceptors expressing the ion channel transient receptor potential cation channel, subfamily V, member 1, play an important role in mediating postoperative pain. Signaling from these nociceptors in the peri- and postoperative period can lead to plastic changes in the spinal cord and, when controlled, […]

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Uncategorized Published - 3 January, 2018    By - Dr Clemens
Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept

Authors: Sheila Riazi, M.Sc., M.D. et al Anesthesiology 1 2018, Vol.128, 168-180 This article reviews advancements in the genetics of malignant hyperthermia, new technologies and approaches for its diagnosis, and the existing limitations of genetic testing for malignant hyperthermia. It also reviews the various RYR1-related disorders and phenotypes, such as myopathies, exertional rhabdomyolysis, and bleeding disorders, and […]

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