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British Journal of Anesthesia March 18 Authors: S.M. Weinstein et al Background Postoperative delirium continues to pose major clinical difficulties. While unmodifiable factors (e.g. age and comorbidity burden) are commonly studied risk factors for delirium, the role of modifiable factors, such as anaesthesia type and commonly used perioperative medications, remains understudied. This study aims to […]
Read MoreAuthors: Xu, Bo MD et al Anesthesia & Analgesia: December 2017 – Volume 125 – Issue 6 – p 1907–1910 To investigate the influence of age on sensitivity to dexmedetomidine sedation in adult patients, we selected 79 patients scheduled for lower limb orthopedic surgery under spinal anesthesia to identify the dexmedetomidine ED50 for adequate sedation among different […]
Read MoreASA Monitor 4 2018, Vol.82, 43. Which of the following has a greater likelihood of being present in a child with laryngotracheobronchitis (croup) than in a child with epiglottitis? Croup is a viral illness most commonly attributed to the following infectious agents: Croup, the most common infectious cause of stridor in children, generally begins as an upper-respiratory tract […]
Read MoreAuthors: Satoshi Suzuki, M.D., Ph.D. et al Anesthesiology March 2018. Background: Intraoperative oxygen management is poorly understood. It was hypothesized that potentially preventable hyperoxemia and substantial oxygen exposure would be common during general anesthesia. Methods: A multicenter, cross-sectional study was conducted to describe current ventilator management, particularly oxygen management, during general anesthesia in Japan. All adult patients (16 […]
Read MoreAuthors: Justyna Bartoszko, M.D. et al Anesthesiology March 2018. Background: Research into major bleeding during cardiac surgery is challenging due to variability in how it is scored. Two consensus-based clinical scores for major bleeding: the Universal definition of perioperative bleeding and the European Coronary Artery Bypass Graft (E-CABG) bleeding severity grade, were compared in this substudy of […]
Read MoreAuthors: Peter Kranke, M.D., M.B.A. et al Anesthesiology published on March 2018 Background: Postoperative nausea and vomiting causes distress for patients and can prolong care requirements. Consensus guidelines recommend use of multiple antiemetics from different mechanistic classes as prophylaxis in patients at high risk of postoperative nausea and vomiting. The prophylactic efficacy of the dopamine D2/D3 antagonist amisulpride […]
Read MoreAuthors: Abirami Kumaresan, M.D. et al Anesthesiology Newly Published on March 8, 2018. Background: The effects of prone positioning on esophageal pressures have not been investigated in mechanically ventilated patients. Our objective was to characterize effects of prone positioning on esophageal pressures, transpulmonary pressure, and lung volume, thereby assessing the potential utility of esophageal pressure measurements in […]
Read MoreAuthor: Lorenzo Di Francesco, MD, FACP, FHM Opioids are not better than nonopioid drugs for relieving back pain or pain related to hip or knee osteoarthritis, a JAMA study finds. Nearly 250 patients with moderate-to-severe chronic back pain or hip or knee osteoarthritis pain were randomized to receive either opioids or nonopioids. In the opioid group, patients […]
Read MoreAuthors: Andra E. Duncan, M.D. et al Anesthesiology published on March 2018 Background: Hyperinsulinemic normoglycemia augments myocardial glucose uptake and utilization. We tested the hypothesis that hyperinsulinemic normoglycemia reduces 30-day mortality and morbidity after cardiac surgery. Methods: This dual-center, parallel-group, superiority trial randomized cardiac surgical patients between August 2007 and March 2015 at the Cleveland Clinic, Cleveland, Ohio, […]
Read MoreAuthors: Ryuhei Araki, M.D. et al Anesthesiology 4 2018, Vol.128, 754-763. Background: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α […]
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