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In patients with rheumatoid arthritis or osteoarthritis at higher risk for cardiovascular events, celecoxib may be safer compared with naproxen or ibuprofen when these drugs are taken alone or in combination with aspirin, according to a study published in Journal of the American College of Cardiology. In this post hoc analysis of a trial that compared 3 nonsteroidal […]
Read MoreAuthors: P. Bąbel MD et al European Journal of Pain 22 December 2017 Background A previous study has shown that memory of pain induced by running a marathon might be underestimated. However, little is known about the factors that might influence such a memory distortion during pain recall. The aim of the study was to investigate […]
Read MoreAuthors: Chu DK et al. Lancet 2018 Apr 28. A meta-analysis shows significantly higher mortality with liberal use of supplemental oxygen in acutely ill patients. Supplemental oxygen can be a life-saving intervention for patients with hypoxemic respiratory failure; however, emerging evidence suggests that too much oxygen is harmful (NEJM JW Gen Med Dec 1 2016 and JAMA 2016; 316:1583). Small […]
Read MoreImplementation of an enhanced recovery program for patients undergoing elective cesarean delivery can improve care without incurring a prohibitive expense for hospitals, a study has concluded. The program might even reduce costs considerably. According to researchers at Saint Peter’s Healthcare System, in New Brunswick, N.J., cost savings associated with a reduction in hospital length of […]
Read MoreThe management of postsurgical pain with patient-controlled analgesia pumps may be safe, as indicated by a low rate of device-related error, according to results from a retrospective study published in Anesthesia & Analgesia. Patient-controlled analgesia infusion pumps are generally considered safe and effective for postoperative pain management but may be associated with human- and device-related errors, which can […]
Read MoreAdding an exercise regimen to a comprehensive educational program for the management of greater trochanteric pain syndrome may not bring significant benefit, according to a randomized controlled trial published in the Journal of Women’s Health. A group of postmenopausal women with lateral hip pain were assigned to follow the Gluteal La Trobe University exercise program (GLoBE; n=38) or […]
Read MoreThe relationship between inflammatory biomarkers and outcomes is not well researched in patients undergoing high-risk, noncardiac procedures. Recent research found that a variety of biomarkers produce a robust response to noncardiac surgery. In particular, they found that both suppression of tumorigenicity 2 (ST2) and interleukin-8 (IL-8) showed discriminatory ability to predict complications in these patients. […]
Read MoreMigraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events, including stroke and myocardial infarction, according to a meta-analysis published in BMJ Open. This systemic review analyzed results from 16 cohort studies, including 394,942 study participants with migraine and 757,465 without migraine. The primary and secondary outcomes were major adverse cardiovascular […]
Read MoreAuthors: Siyi Yan et al Journal Clinical Anesthesia June 2018 Volume 47 Pages 74-79 Study objective There is controversy regarding the efficacy and safety of using interscalene block (ISB) combined with general anesthesia (GA) for arthroscopic shoulder surgery. Our meta-analysis was undertaken to evaluate the utility of this approach. Measurements We searched the PubMed, Cochrane […]
Read MoreAuthor: Sulagna Bhattacharjee Journal of Clinical Anesthesia June 2018 Volume 47 Pages 54-59 Possible advantages and risks associated with ultrasound guided radial artery cannulation in-comparison to digital palpation guided method in adult patients are not fully known. We have compared ultrasound guided radial artery cannulation with digital palpation technique in this meta-analysis. Design Meta-analysis of […]
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