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A new study suggests that the association of sodium intake with cardiovascular disease (CVD) is valid only when mean intake is greater than 5 g/day, and with lower intake, the inverse relationship may be true. Researchers at McMaster University (Hamilton, ON, Canada), King Saud University (KSU; Riyadh, Saudi Arabia), Aga Khan University (Karachi, Pakistan), and […]
Read MoreThe use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission, according to a recent study published in British Journal of Anaesthesia. The registry data of 153,902 patients (ambulatory surgery, n=40,060; non-ambulatory surgery, n=113,842) who underwent surgery with general anesthesia at 3 hospitals, including Massachusetts General […]
Read MoreSciatic nerve block may represent an effective complement to femoral nerve block for total knee arthroplasty, particularly in patients at high risk for postoperative opioid use, according to a systematic literature review published in Journal of Anesthesia. Researchers conducted a meta-analysis of prospective randomized studies comparing femoral plus sciatic nerve blocks vs femoral nerve block alone for total […]
Read MoreAuthors: Nicholas Heming, M.D., Ph.D. et al Anesthesiology published September 12, 2018. What We Already Know about This Topic: Whether crystalloid or colloids are preferable for treatment of hypovolemic shock in surgical patients remains unclear What This Article Tells Us That Is New: In a preplanned subgroup analysis of a previous trial, the authors compared 28-day […]
Read MoreN.H. Sperna Weiland et al,Authors: N. H,Background The baroreflex regulates arterial blood pressure (BP). During periods when blood pressure changes, cerebral blood flow (CBF) is kept constant by cerebral autoregulation (CA). In patients with diabetes mellitus (DM), low baroreflex sensitivity (BRS) is associated with impaired CA. As sevoflurane-based anaesthesia obliterates BRS, we hypothesised that this […]
Read MoreThe FDA has approved fremanezumab (marketed as Ajovy) to prevent migraine in adults. The injectable drug, given monthly or quarterly, is a humanized monoclonal antibody that targets calcitonin gene-related peptide. In phase III trials among adults with disabling migraine, fremanezumab reduced the number of monthly migraine days over 12 weeks relative to placebo. It was […]
Read MoreAuthors: S. Boet et al British Journal of Anesthesia Sept 2018 Background Non-technical skills, such as communication or leadership, are integral to clinical competence in anaesthesia. There is a need for valid and reliable tools to measure anaesthetists’ non-technical performance for both initial and continuing professional development. This systematic review aims to summarise the measurement […]
Read MoreA commonly used painkiller might be too risky for people to keep taking, suggests a new study published this week in the BMJ. It found that people who use diclofenac, a non-steroidal anti-inflammatory drug (NSAID), are more likely to come down with cardiovascular disease than people who take other NSAIDs or acetaminophen. Diclofenac is sold under […]
Read MoreAuthors: Zannad F et al. N Engl J Med 2018 Aug 27 A randomized trial found no improvement in outcomes with low-dose rivaroxaban. Chronic anticoagulation in patients with heart failure and reduced ejection fraction (HFrEF), but without atrial fibrillation (Afib, AF), has long been controversial; clinical trials have not demonstrated any benefit of warfarin use. This […]
Read MoreWritten by Julie Spitzer | Becker’s Hospital Review August 30, 2018 | Fifty-seven percent of Americans say they’ve received a surprise medical bill they thought would be covered by insurance, according to a recent survey conducted by NORC at the University of Chicago. NORC polled 1,002 individuals from a nationally representative sample of Americans using the AmeriSpeak Panel, a […]
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