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Authors: Sérgio M. Pereira, M.D. et al Anesthesiology published September 2018. What We Already Know about This Topic: In patients with adult respiratory distress syndrome, physiologic tidal volume and positive end-expiratory pressure (PEEP) are protective In patients without lung diseases undergoing mechanical ventilation under general anesthesia, optimal PEEP is unknown What This Article Tells Us That […]
Read MoreAntibiotic therapy alone appears to be feasible for the initial treatment of uncomplicated appendicitis in adults, according to longer-term follow-up from the APPAC trial, published in JAMA. Roughly 530 adults with uncomplicated acute appendicitis confirmed on computed tomography were randomized to appendectomy or antibiotics. The latter entailed intravenous ertapenem for 3 days, followed by oral levofloxacin […]
Read MoreAuthor: Ingrid Stiver Senior Manager, PwC Health Research Institute, PwC US August 29, 2018 PwC’s Health Research Institute (HRI) projects a 6 percent medical cost trend in 2019, consistent with the 5.5-7 percent range of the previous five years. But employers continue to struggle to contain their employee coverage costs. Medical costs continue to grow, yet the […]
Read MoreAuthors: Feras Hatib, Ph.D. et al Anesthesiology 10 2018, Vol.129, 663-674. What We Already Know about This Topic: The ability to predict intraoperative hypotension may advance the ability to prevent hypotension-associated complications effectively The extent to which advanced waveform analysis of invasive arterial lines may provide meaningful forewarning remains unknown What This Article Tells Us That […]
Read MoreAuthors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. Anesthesiology published September 2018. What We Already Know about This Topic: Neuraxial anesthesia use for hip fracture surgery has wide variation in use across hospitals, and hospitals using it for less than 25% of patients may have increased 30-day mortality The proportion of the variation in use attributable to […]
Read MoreAuthors: Naveed Liquidize, M.D., M.Sc. et al Anesthesiology published September 2018. What We Already Know about This Topic: Accurate identification of the cricothyroid membrane is key for success of emergency cricothyrotomy Ultrasound has been reported to identify the cricothyroid membrane more accurately than external palpation in patients with normal neck anatomy What This Article Tells Us […]
Read MoreAuthors: Philippe Biboulet, M.D. et al Anesthesiology 10 2018, Vol.129, 710-720. Editor’s Perspective: What We Already Know about This Topic: Epoetin-α is often given to patients scheduled for major orthopedic surgery It remains unknown whether it is best to accompany epoetin-α with oral or intravenous iron What This Article Tells Us That Is New: Hemoglobin level […]
Read MoreAuthors: Anthony G. Doufas, M.D., Ph.D. et al Anesthesiology published September 2018. What We Already Know about This Topic: Patients with obstructive sleep apnea are often said to have increased sensitivity to opioid-induced ventilatory depression What This Article Tells Us That Is New: The hypothesis that patients with moderate-to-severe obstructive sleep apnea are more sensitive to […]
Read MoreAuthors: Béatrice La Combe, M.D., M.Sc. et al Anesthesiology published September 2018. What We Already Know about This Topic: Chlorhexidine is frequently used to reduce oropharyngeal bacterial colonization in mechanically ventilated patients. How effective the drug is remains unclear. What This Article Tells Us That Is New: Bacterial colonization was evaluated in 30 mechanically ventilated patients […]
Read MoreAuthors: Francesca Campoccia Jalde, M.D., Ph.D. et al Anesthesiology 10 2018, Vol.129, 769-777. What We Already Know about This Topic: Neurally adjusted ventilatory assist matches the mechanical pressure from the ventilator to the patient’s respiratory drive sensed from the electrical activity of the diaphragm, but the optimal degree of diaphragm unloading is uncertain What This Article […]
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