-
-
Call more information
660-596-2224 -
Authors: O’Carroll J et al. Anesthesiology 144(4):784–795, April 2026 Summary:This large prospective multicenter cohort study provides one of the most definitive assessments to date of intraoperative pain during cesarean delivery under neuraxial anesthesia. Across 15 centers in the United States and Canada, nearly 3,700 patients were surveyed on postoperative day 1, capturing patient-reported pain and […]
Read MoreAuthors: Kawashima S et al. Anesthesiology 144(4):1027–1028, April 2026 Summary:This letter critiques a prior in vitro study examining the effects of Propofol, Dexmedetomidine, and Acetaminophen on skeletal muscle under hyperthermic conditions. While acknowledging the mechanistic value of the work, the authors emphasize that several key limitations reduce its clinical applicability. The primary concern is the […]
Read MoreAuthors: Eaton M et al. Anesthesiology 144(4):1029–1030, April 2026 Summary:This reply addresses concerns raised about the use of Dabigatran with Idarucizumab for cardiopulmonary bypass (CPB) anticoagulation. The authors acknowledge the limitations highlighted in the prior commentary and emphasize that this work remains in an early, preclinical stage of development. They agree that defining the minimum […]
Read MoreAuthors: Zhu X et al. Anesthesiology 144(4):1028–1029, April 2026 Summary:This commentary evaluates a novel anticoagulation strategy for cardiopulmonary bypass (CPB) using Dabigatran with reversal by Idarucizumab. The authors highlight the potential importance of this approach, particularly for patients with heparin-induced thrombocytopenia, where current options are limited. The first major issue raised is dosing. Although the […]
Read MoreAuthors: Huber M Anesthesiology 144(4):1016–1020, April 2026 Summary:This article introduces Bayesian statistical approaches as a complement to traditional frequentist methods in analyzing randomized controlled trials. It focuses on two key Bayesian indices—probability of direction and region of practical equivalence (ROPE)—to provide a more clinically meaningful interpretation of study results. The probability of direction reflects how […]
Read MoreBurnout or time away in pain, ICU, or administration doesn’t erase your anesthesia training—it just requires a structured path back. For many physicians, it simply means you stepped away to regroup. We work with anesthesiologists every day who want to return to clinical anesthesia after time away in: administration or leadership roles pain medicine critical […]
Read MoreAuthors: Huang D et al. Anesthesiology 144(4):1021–1024, April 2026 Summary:This prospective exploratory study evaluates a novel general anesthesia strategy using Remifentanil and Esketamine for deep-brain stimulation (DBS) surgery in patients with Parkinson disease. Traditionally, DBS electrode placement is performed under awake or lightly sedated conditions to preserve microelectrode recording signals, but this approach can be […]
Read MoreAuthors: Wang J et al. Anesthesiology 144(4):886–897, April 2026 Summary:This large retrospective cohort study evaluates whether critical closing pressure (Pcc) and tissue perfusion pressure (TPP) provide better prognostic insight than mean arterial pressure (MAP) alone in patients with sepsis. While MAP has traditionally been the primary target for resuscitation, it does not fully capture the […]
Read MoreAuthors: Asif H et al. Anesthesiology 144(4):1012–1015, April 2026 Summary:This exploratory study examines how intraoperative variables affect spinal cord blood flow (SCBF) in humans using laser speckle contrast imaging, a technique that provides real-time, high-resolution perfusion mapping during spinal surgery. The key finding is that spinal cord blood flow behaves differently from cerebral blood flow […]
Read MoreAuthors: Douville N et al. Anesthesiology 144(4):1026–1027, April 2026 Summary:This reply reinforces and expands on the argument that traditional hemodynamic parameters are inadequate for assessing anesthetic depth, agreeing with prior commentary that blood pressure and heart rate reflect secondary physiologic responses rather than direct brain effects. The authors emphasize that anesthetic depth should be grounded […]
Read More