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Uncategorized Published - 12 August, 2022    By - Dr Clemens
Interactions of the protease inhibitor, ritonavir, with common anesthesia drugs

DG Journal Club Anders Svedmyr, Henrik Hack, Brian J Anderson Paediatr Anaesth. 2022 Jul 17 The protease inhibitor, ritonavir, is a strong inhibitor of CYP 3A. The drug is used for management of the human immunovirus and is currently part of an oral antiviral drug combination (nirmatrelvir-ritonavir) for the early treatment of SARS-2 COVID-19-positive patients […]

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Uncategorized Published - 12 August, 2022    By - Dr Clemens
Best pain medication for severe arthritis

Author: Suchandrima Bhowmik MedicalNewsToday Arthritis is a chronic inflammation of the joint that affects people worldwide. Doctors will create treatment plans for people based on the level of pain they experience, such as those with severe arthritis. According to the Centers for Disease Control and Prevention (CDC), 58.5 million people in the United States have arthritis. The Arthritis […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
Reduction of Nonoperative Time Using the Induction Room, Parallel Processing, and Sugammadex

AUTHORS: Kaddoum, Roland MD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 406-413 BACKGROUND: An important variable in the operating room is the nonoperative time (NOT), the time between skin closure on a previous case and skin incision on the following case. Mismanagement of NOT can result in significant […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
“My Surgical Success”: Feasibility and Impact of a Single-Session Digital Behavioral Pain Medicine Intervention on Pain Intensity, Pain Catastrophizing, and Time to Opioid Cessation After Orthopedic Trauma Surgery

AUTHORS: Ziadni, Maisa S. PhD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 394-405 BACKGROUND: Behavioral pain treatments may improve postsurgical analgesia and recovery; however, effective and scalable options are not widely available. This study tested a digital perioperative behavioral medicine intervention in orthopedic trauma surgery patients for feasibility […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
Platelet Transfusion and Outcomes After Massive Transfusion Protocol Activation for Major Trauma

AUTHORS: Aichholz, Pudkrong K. MD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 385-393 BACKGROUND:  Incorporation of massive transfusion protocols (MTPs) into acute major trauma care has reduced hemorrhagic mortality, but the threshold and timing of platelet transfusion in MTP are controversial. This study aimed to describe early (first […]

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