⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Uncategorized Published - 2 December, 2022    By - Dr Clemens
Opioids: The Elephant in the Room

“Empire of Pain: The Secret History of the Sackler Dynasty” By Radden Keefe Patrick, New York Doubleday 2021 Pages: 560. ISBN 978-0-385-54568-6. Price: $21 (Hardcover); $15.99 (Kindle Edition). “Dopesick: Dealers, Doctors, and the Drug Company that Addicted America” By Macy Beth, New York,  Little Brown and Company, 2018 . Pages: 400. ISBN 978-0-316-55128-1. Price: $29.69 […]

Read More
Uncategorized Published - 2 December, 2022    By - Dr Clemens
CRPS and Non-Conventional Pharmacological Therapies

Authors: Tran D, Ferguson M. Pract Pain Manag. 2022 September/October;22(5). CRPS: A Brief Background Complex regional pain syndrome (CRPS) is a chronic neuro-inflammatory disorder that affects one or more extremities, usually following surgery, injury, or trauma, but also occurs spontaneously. The pathophysiology of CRPS is complex and poorly understood; therefore, well-defined criteria for diagnosis are […]

Read More
Uncategorized Published - 2 December, 2022    By - Dr Clemens
Biased Signaling in G-Protein-Coupled Receptors: The μ Opioid Receptor

Authors: Richard Simoneaux; Steven L. Shafer, MD, FASA ASA Monitor October 2022, Vol. 86, 1–8. In 2012, the Nobel Prize in Chemistry was awarded to Robert J. Lefkowitz, Howard Hughes Medical Institute/Duke University Medical Center, and Brian K. Kobilka, Stanford University School of Medicine, for “groundbreaking discoveries that reveal the inner workings of… G-protein-coupled receptors” (asamonitor.pub/3Cb1vVL). G-protein-coupled […]

Read More
Uncategorized Published - 2 December, 2022    By - Dr Clemens
Bridging the Workforce Gap

#TheAnesthesiaBlog Increasing numbers of NHS consultants are voluntarily reducing their time spent delivering contracted direct clinical care. The result is concerning, with experienced clinicians working less hours and retiring early. This new guidance aims to highlight contributory issues and list clear, implementable solutions. One theme is that ‘age’ in anaesthesia should not be perceived negatively […]

Read More
Uncategorized Published - 1 December, 2022    By - Dr Clemens
Preoperative Ultrasound-guided Percutaneous Cryoneurolysis for the Treatment of Pain after Mastectomy

Authors: Brian M. Ilfeld, M.D., M.S. et al  Anesthesiology November 2022, Vol. 137, 529–542. Background Ultrasound-guided percutaneous cryoneurolysis is an analgesic technique in which a percutaneous probe is used to reversibly ablate a peripheral nerve(s) using exceptionally low temperature, and has yet to be evaluated with randomized, controlled trials. Pain after mastectomy can be difficult to […]

Read More