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Uncategorized Published - 15 December, 2022    By - Dr Clemens
Opioid-Induced Adrenal Insufficiency

Authors: Bush DA, Barbero E. Pract Pain Manag. 2022 September/October;22(5). About Opioid Induced Adrenal Insufficiency Opioid induced adrenal insufficiency (OIAI) is a complication of opioid use that is less well known than other known complications of opioid use such as constipation, respiratory depression, and addiction. OIAI however has been shown to be a consequence of […]

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Uncategorized Published - 15 December, 2022    By - Dr Clemens
Chronic Pain in Children: How to Lead a Clinical Conversation

Authors: Weston G, Sweeney M, Zeltzer L. Pract Pain Manag. 2022 November/December;22(6). When children come to your office due to persistent or chronic pain, odds are that you are not going to be their first experience with the medical field. They have, most likely, already filled out questionnaires, participated in assessments, undergone a variety of […]

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Uncategorized Published - 15 December, 2022    By - Dr Clemens
Finding a Path to Reducing Disparities and Measuring Health Equity

Authors: Matthew T. Popovich, PhD; Claire Ostarello, CPHQ ASA Monitor November 2022, Vol. 86, 39–40. Although health disparities have long existed, the COVID-19 pandemic in 2020 focused the general public, health care leaders, and patient advocates on identifying pathways to reduce disparities and improve health equity. For anesthesiologists and their groups, reducing disparities and contributing to greater […]

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Uncategorized Published - 14 December, 2022    By - Dr Clemens
What medication options exist for migraine prophylaxis when solid oral dosage forms cannot be administered?

Author: Holshouser B et al Pract Pain Manag. 2022 September/October;22(5). For children and adolescents, the prevalence of migraine by age 15 is 8% to 23%, and around 38.8% of Americans age 12 and older should be offered or considered for preventive migraine treatment.¹˒² Due to the debilitating nature of migraine disorder, it is important to […]

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Uncategorized Published - 14 December, 2022    By - Dr Clemens
Local Anesthetic Cardiac Toxicity Is Mediated by Cardiomyocyte Calcium Dynamics

Authors: Julia Plakhotnik, B.Sc. et al  Anesthesiology December 2022, Vol. 137, 687–703. Background Long-lasting local anesthetic use for perioperative pain control is limited by possible cardiotoxicity (e.g., arrhythmias and contractile depression), potentially leading to cardiac arrest. Off-target cardiac sodium channel blockade is considered the canonical mechanism behind cardiotoxicity; however, it does not fully explain the observed […]

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