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Uncategorized Published - 13 January, 2023    By - Dr Clemens
Cold-stored Platelets for Bleeding Patients: Comment

Authors: Warren Choi, M.D.; Yafen Liang, M.D. Anesthesiology December 2022. To the Editor: We read with great interest the recent article published in Anesthesiology by Strandenes et al., titled “A Pilot Trial of Platelets Stored Cold versus at Room Temperature for Complex Cardiothoracic Surgery.”  We congratulate the authors on their pioneering work in the field of transfusion medicine and efforts to identify methods […]

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Uncategorized Published - 13 January, 2023    By - Dr Clemens
Predicting Intensive Care Delirium with Machine Learning: Model Development and External Validation

Authors: Kirby D. Gong, MSE et al  Anesthesiology December 2022. Background Delirium poses significant risks to patients, but countermeasures can be taken to mitigate negative outcomes. Accurately forecasting delirium in ICU patients could guide proactive intervention. Our primary objective was to predict ICU delirium by applying machine learning to clinical and physiological data routinely collected […]

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Uncategorized Published - 13 January, 2023    By - Dr Clemens
Risk Factors for Early Appendectomy After Initial Antibiotic Treatment for Appendicitis

NEJM Journal Watch Thomas L. Schwenk, MD, reviewing Writing Group for the CODA Collaborative. JAMA Surg 2022 Jan 12 Feldman LS and Lee L. JAMA Surg 2022 Jan 12 The presence of an appendicolith doubled the likelihood of subsequent appendectomy. In a recent study, appendiceal diameter of ≥15 mm or fever >38°C predicted early failure of antibiotic therapy for uncomplicated […]

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Uncategorized Published - 12 January, 2023    By - Dr Clemens
Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia

Authors: Hyun-Jung Shin, M.D., Ph.D. et al  Anesthesiology December 2022. Background Delirium is a critical postoperative complication in older patients. Based on the hypothesis that intraoperative dexmedetomidine sedation would lower postoperative delirium than propofol sedation would, the authors compared the incidence of postoperative delirium in older adults, using the mentioned sedatives. Methods This double-blinded, randomized […]

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Uncategorized Published - 12 January, 2023    By - Dr Clemens
Analgesics Drug Report 2022: The Pain Management Pipeline

Authors: Jacquot M, Klinefelter et al Pract Pain Manag. 2023 January/February;23(1). With more than 1 in 5 Americans experiencing chronic pain, pain management is an important area of clinical research.¹ Ongoing studies are aimed at developing safe and effective analgesic drugs with a low risk of addiction and overdose.² In late 2022, an update to […]

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