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Uncategorized Published - 18 January, 2023    By - Dr Clemens
Salted or sweet? Hypertonic saline or mannitol for treatment of intracranial hypertension

Authors: Lamperti, Massimo et al Anaesthesiology 35(5):p 555-561, October 2022.  Purpose of review The aim of this review article is to present current recommendations regarding the use of hypertonic saline and mannitol for the treatment of intracranial hypertension. Recent findings In recent years, a significant number of studies have been published comparing hypertonic saline with mannitol in patients with […]

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Uncategorized Published - 18 January, 2023    By - Dr Clemens
How to Talk to Patients about Addiction

Author: Li B, Moukaddam N. Pract Pain Manag. 2023 January/February;23(1). Background In the journey to help patients recover from chronic pain and disability, clinicians must be vigilant for signs of an evolving opioid use disorder (OUD). It is not uncommon for a pain practice to inherit patients with a pre-existing OUD, but it is also […]

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Uncategorized Published - 18 January, 2023    By - Dr Clemens
Wellness and Coping of Physicians Who Worked in ICUs During the Pandemic

AUTHORS: Burns, Karen E. A. MD et al Critical Care Medicine 50(12):p 1689-1700, December 2022 OBJECTIVES:  Few surveys have focused on physician moral distress, burnout, and professional fulfilment. We assessed physician wellness and coping during the COVID-19 pandemic. DESIGN: Cross-sectional survey using four validated instruments. SETTING: Sixty-two sites in Canada and the United States. SUBJECTS: Attending physicians (adult, […]

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Uncategorized Published - 17 January, 2023    By - Dr Clemens
Effect of Preoperative Oral Saline Administration on Postoperative Delirium in Older Persons

DG Journal Club Authors: Jinzhuan Chen, Siyu Xie, Ying Chen, Ting Qiu Clin Interv Aging. 2022; 17 1539-1548 Objective Postoperative delirium (POD) seriously affects recovery of older persons, increasing their mortality rate after surgery. We aimed to evaluate preoperative oral saline administration on postoperative delirium in older persons undergoing spinal decompression. Design A randomised controlled […]

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Uncategorized Published - 17 January, 2023    By - Dr Clemens
Derivation and Validation of Clinical Phenotypes of the Cardiopulmonary Bypass–Induced Inflammatory Response

AUTHORS: Milam, Adam J. MD, PhD et al  Anesthesia & Analgesia November 04, 2022. BACKGROUND: Precision medicine aims to change treatment from a “one-size-fits-all” approach to customized therapies based on the individual patient. Applying a precision medicine approach to a heterogeneous condition, such as the cardiopulmonary bypass (CPB)–induced inflammatory response, first requires identification of homogeneous subgroups […]

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