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Uncategorized Published - 20 February, 2023    By - Dr Clemens
Identification of Preanesthetic History Elements by a Natural Language Processing Engine

AUTHORS: Suh, Harrison S. BS et al  Anesthesia & Analgesia 135(6):p 1162-1171, December 2022. BACKGROUND: Methods that can automate, support, and streamline the preanesthesia evaluation process may improve resource utilization and efficiency. Natural language processing (NLP) involves the extraction of relevant information from unstructured text data. We describe the utilization of a clinical NLP pipeline intended […]

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Uncategorized Published - 20 February, 2023    By - Dr Clemens
Brain Cancer Progression: A Retrospective Multicenter Comparison of Awake Craniotomy Versus General Anesthesia in High-grade Glioma Resection

Authors: Chowdhury, Tumul MD, DM, FRCPC et al Journal of Neurosurgical Anesthesiology 34(4):p 392-400, October 2022. Background: High-grade gliomas impose substantial morbidity and mortality due to rapid cancer progression and recurrence. Factors such as surgery, chemotherapy and radiotherapy remain the cornerstones for treatment of brain cancer and brain cancer research. The role of anesthetics on glioma progression is largely unknown. Methods: This […]

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Uncategorized Published - 20 February, 2023    By - Dr Clemens
Whole-organ deceased donor tracheal allograft transplantation for the treatment of refractory tracheal stenosis: a case report

Authors: Dickerson, Shane C. MD et al  Journal of Head & Neck Anesthesia 6(1):p e41, May 2022. Abstract Tracheal stenosis involving >5 cm of trachea is debilitating for patients, impedes their quality of life and may even become life-threatening. Large, open defects often result in these patients because of multiple failed tracheal resections and endoscopic dilatations. Tracheal transplantation […]

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Uncategorized Published - 20 February, 2023    By - Dr Clemens
Brain-specific genes contribute to chronic but not to acute back pain

Authors: Bortsov, Andrey V. et al  PAIN Reports 7(5):p e1018, September/October 2022. Introduction: Back pain is the leading cause of disability worldwide. Although most back pain cases are acute, 20% of acute pain patients experience chronic back pain symptoms. It is unclear whether acute pain and chronic pain have similar or distinct underlying genetic mechanisms. Objectives: […]

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Uncategorized Published - 17 February, 2023    By - Dr Clemens
Cerebral metabolic derangements following traumatic brain injury

Authors: Demers-Marcil, Simona,b; Coles, Jonathan P.a Anaesthesiology 35(5):p 562-569, October 2022.  Summary Mitochondrial dysfunction and the use of alternative energy substrates are potential therapeutic targets, but improved understanding of the causes, impact and significance of metabolic derangements in clinical TBI are needed. Maintaining adequate oxygen and glucose delivery across the injured brain may accelerate the […]

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