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Anesthesiology Published - 22 September, 2025    By - Dr Clemens
Acute Pain After Total Knee Arthroplasty: 2-Arachidonoylglycerol Tone and Endocannabinoid/Eicosanoid Crosstalk

Authors: Schutz L et al Anesthesia & Analgesia. September 09, 2025. doi:10.1213/ANE.0000000000007741 This prospective study investigated whether intraoperative levels of the endocannabinoid 2-arachidonoylglycerol (2-AG) are associated with acute postoperative pain after total knee arthroplasty (TKA). Ninety patients were enrolled, and 2-AG levels were measured in synovial fluid (SF) and cerebrospinal fluid (CSF). Higher SF 2-AG […]

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Anesthesiology Published - 22 September, 2025    By - Dr Clemens
ASCs’ new CRNA playbook

Author: Patsy Newitt Becker’s ASC Review ASCs are rewriting the anesthesia playbook, leaning more heavily on certified registered nurse anesthetists amid economic pressures and staffing shortages. The rise of CRNA-only ASCs Across the U.S., many ASCs are transitioning away from physician-supervised anesthesia to CRNA-only care. A white paper from Medicus Healthcare Solutions found that 75% of CRNAs reported practicing […]

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Anesthesiology Published - 19 September, 2025    By - Dr Clemens
Opioid-Restricting Protocol Reduces Chronic Opioid Use

Authors: Woodmass J, et al. Canadian Journal of Surgery. Published June 18, 2025. This large pre-post intervention study evaluated the effect of an opioid-sparing protocol combining structured patient education with scheduled nonopioid analgesia (acetaminophen and ibuprofen), supplemented by tramadol for breakthrough pain, in outpatient orthopedic surgery patients. The analysis included over 10,000 opioid-naive patients undergoing […]

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Anesthesiology Published - 19 September, 2025    By - Dr Clemens
Low-Dose Epidural Dexmedetomidine as an Adjuvant to Bupivacaine Versus Conventional Bupivacaine for Postoperative Analgesia

Authors: Sabu N, Meshram S, Chavan G Cureus 17(9): e92018. doi:10.7759/cureus.92018 This randomized controlled trial compared low-dose epidural dexmedetomidine combined with 0.0625% bupivacaine (Group BD) against conventional 0.125% bupivacaine alone (Group BB) in 120 ASA I–II adults undergoing abdominal and lower limb surgeries. Patients in the dexmedetomidine group required fewer rescue analgesics and demonstrated significantly […]

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Anesthesiology Published - 19 September, 2025    By - Dr Clemens
CRNA pay: 5 things to know

Author: Sophie Eydis Becker’s ASC Review Certified registered nurse anesthetists remain among the highest-paid advanced practice providers in the U.S., with average annual salaries topping $214,000. But pay varies widely depending on practice setting, location and employment structure. Here are five key stats on where CRNA compensation stands in 2025: 1. Average pay remains above […]

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