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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Motor Vehicle Crash Risk among Adults Undergoing General Surgery 2023

Authors: Timothy G. Gaulton, M.D., M.Sc. et al  Anesthesiology June 2023, Vol. 138, 602–610. Background Surgery causes transient impairment in cognition and function, which may impact driving safety. The authors hypothesized that the risk of a motor vehicle crash would increase after compared to before surgery. Methods The authors performed a nested case-crossover study within population-based […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Layering Migraine Medications Leads to More Effective Relief 2023

Author: Doheny K. Pract Pain Manag. 2023 May/June;22(3). With additional medications now FDA-approved and available, combination therapy promises to give more patients improved outcomes. It’s an old concept in migraine management that’s been given a new name in recent years: layering. “Conceptually, it’s nothing new,” said Jay Joshi, MD, DABA, DABA-PM, FABA-PM, CEO and medical […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Prevalence and Risk Factors for Chronic Post-Surgical Pain Following Cardiac Surgery 2023

Authors: Maggie ZX Xiao, BSc et al  Anesthesiology May 2023. Background Chronic post-surgical pain is a common complication of surgery. The role of psychological risk factors like depression and anxiety is substantially understudied in cardiac surgery. This study sought to identify perioperative factors associated with chronic pain at 3, 6, and 12 months after cardiac […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain 2023

Authors: Clemens Reiffurth, Ph.D. et al  Anesthesiology June 2023, Vol. 138, 611–623. Background Maintenance of ion homeostasis is essential for normal brain function. Inhalational anesthetics are known to act on various receptors, but their effects on ion homeostatic systems, such as sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase), remain largely unexplored. Based on reports demonstrating global network activity and wakefulness […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Chronic Pain at the Pharmacy: Methadone Initiation for CRPS and Comorbidities

Author: Amarquaye W. Pract Pain Manag. 2023 May/June;23(3). When a patient asks about beginning methadone therapy for CRPS, clinical pharmacist William Amarquaye advises on administration, titration, side effects, and interactions. Patient Scenario: Patient Prescribed Methadone for CRPS The Patient Patient Bob* called our pharmacy inquiring about a new prescription for methadone that he was placed […]

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