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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain 2023

Authors: Clemens Reiffurth, Ph.D. et al  Anesthesiology June 2023, Vol. 138, 611–623. Background Maintenance of ion homeostasis is essential for normal brain function. Inhalational anesthetics are known to act on various receptors, but their effects on ion homeostatic systems, such as sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase), remain largely unexplored. Based on reports demonstrating global network activity and wakefulness […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Chronic Pain at the Pharmacy: Methadone Initiation for CRPS and Comorbidities

Author: Amarquaye W. Pract Pain Manag. 2023 May/June;23(3). When a patient asks about beginning methadone therapy for CRPS, clinical pharmacist William Amarquaye advises on administration, titration, side effects, and interactions. Patient Scenario: Patient Prescribed Methadone for CRPS The Patient Patient Bob* called our pharmacy inquiring about a new prescription for methadone that he was placed […]

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Uncategorized Published - 29 May, 2023    By - Dr Clemens
Happy Memorial Day

Happy Memorial Day! May we never forget those who made the ultimate sacrifice for our freedom. Enjoy the day with your loved ones, and don’t forget to think about those who served and sacrificed. Happy Memorial Day!

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Attributable perioperative cost of frailty after major, elective non-cardiac surgery 2023

Authors: Ryan McGinn, MD MSc et al  Anesthesiology May 2023. Background Patients with frailty consistently experience higher rates of perioperative morbidity and mortality; however, costs attributable to frailty remain poorly defined. We sought to identify older patients with and without frailty using a validated, multidimensional frailty index and estimated the attributable costs in the year […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Assessing Potentially Modifiable Factors Associated with the Development of Postoperative Delirium

Authors: Jeanna D. Blitz, MD, FASA et al  ASA Monitor March 2023, Vol. 87, 27–28. Brain health is inextricably linked with overall physical health. Evidence for the mind-body connection and the bi-directional relationship between them continues to emerge. The past decade has also seen the emergence of a focus on multifactorial quality and outcomes metrics within […]

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