Authors: Acharya, Mahip PhD et al The Clinical Journal of Pain 39(3):p 107-118, March 2023. Objective: To compare the safety profiles of low and high-dose tramadol, short-acting hydrocodone, and short-acting oxycodone therapies among chronic noncancer pain individuals. Materials and Methods: A retrospective cohort study of individuals with back/neck pain/osteoarthritis with an initial opioid prescription for tramadol, hydrocodone, or oxycodone was conducted using IQVIA PharMetrics […]
Read MoreAUTHORS: Belin, Olivier MD et al Anesthesia & Analgesia 136(3):p 540-550, March 2023. BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered […]
Read MoreAUTHORS: Brown, Sydney E. S. MD, PhD et al Anesthesia & Analgesia 136(6):p 1133-1142, June 2023. BACKGROUND: Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk. Empiric differences between patients with and without these devices and […]
Read MoreAUTHORS: Guessous, K. MD et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: Preoperative abnormal cognitive status is a risk factor for postoperative complications yet remains underdiagnosed. During propofol general anesthesia, intraoperative electroencephalography (EEG) variables, such as alpha band power (α-BP), correlate with cognitive status. This relationship under sevoflurane is unclear. We investigated whether […]
Read MoreAUTHORS: Jin, Sherry Y. FRCPC et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: The incidence of failed spinal anesthesia varies widely in the obstetric literature. Although many risk factors have been suggested, their relative predictive value is unknown. The primary objective of this retrospective cohort study was to determine the incidence of failed spinal […]
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