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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Ultramassive Transfusion for Trauma in the Age of Hemostatic Resuscitation

AUTHORS: Muldowney, Maeve MB, BCh, BAO et al  Anesthesia & Analgesia 136(5):p 927-933, May 2023. BACKGROUND: Uncontrolled bleeding is a leading cause of death in trauma. In the last 40 years, ultramassive transfusion (UMT; ≥20 units of red blood cells [RBCs]/24 hours) for trauma has been associated with 50% to 80% mortality; the question remains as […]

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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Peripheral Intravenous Waveform Analysis Responsiveness to Subclinical Hemorrhage in a Rat Model

AUTHORS: Barajas, Matthew B. MD et al  Anesthesia & Analgesia 136(5):p 941-948, May 2023. BACKGROUND: Early detection and quantification of perioperative hemorrhage remains challenging. Peripheral intravenous waveform analysis (PIVA) is a novel method that uses a standard intravenous catheter to detect interval hemorrhage. We hypothesize that subclinical blood loss of 2% of the estimated blood volume […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
In Vitro Analysis of Platelet Adhesion, Aggregation, and Surface GP1bα Expression in Stored Refrigerated Whole Blood

AUTHORS: Keneally, Ryan J. MD et al  Anesthesia & Analgesia 136(5):p 920-926, May 2023. BACKGROUND:  Warm, fresh whole blood (WB) has been used by the US military to treat casualties in Iraq and Afghanistan. Based on data in that setting, cold-stored WB has been used to treat hemorrhagic shock and severe bleeding in civilian trauma patients […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage

AUTHORS: Bandyopadhyay, Anjishnujit DM et al  Anesthesia & Analgesia 136(5):p 913-919, May 2023. BACKGROUND: Critically injured patients who are agitated and delirious on arrival do not allow optimal preoxygenation in the emergency area. We investigated whether the administration of intravenous (IV) ketamine 3 minutes before administration of a muscle relaxant is associated with better oxygen saturation […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Transnasal Videoendoscopy for Preoperative Airway Risk Stratification

AUTHORS: Barclay-Steuart, Alexander MD, MBA et al  Anesthesia & Analgesia 136(6):p 1164-1173, June 2023. | BACKGROUND: Transnasal flexible videoendoscopy (TVE) of the larynx is a standard of care for the detection and staging of pharyngolaryngeal lesions in otorhinolaryngology. Patients frequently present with existing TVE examinations before anesthesia. Although these patients are considered high risk, the diagnostic value […]

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