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Uncategorized Published - 20 October, 2023    By - Dr Clemens
Transplantation Outcomes with Donor Hearts after Circulatory Death

Authors: Jacob N Schroder et al N Engl J Med 2023 Jun 8;388(23):2121-2131 Background: Data showing the efficacy and safety of the transplantation of hearts obtained from donors after circulatory death as compared with hearts obtained from donors after brain death are limited. Methods: We conducted a randomized, noninferiority trial in which adult candidates for heart transplantation […]

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Uncategorized Published - 19 October, 2023    By - Dr Clemens
Velo-epiglottic Adhesion: An Unusual Finding in a Mallampati Zero Airway

Authors: Peter L. Kovacs, M.D. et al  Anesthesiology November 2023, Vol. 139, 664. The figure is from the preanesthetic airway assessment of a 56-yr-old man scheduled for laparoscopic hernia repair. His epiglottis was visible on tongue protrusion (unusual “Mallampati Zero” classification) and was adhered to the uvula as well. The patient related an uneventful past surgical history, although […]

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Uncategorized Published - 19 October, 2023    By - Dr Clemens
Prehospital Tranexamic Acid for Severe Trauma

Authors:  Russell L Gruen et al   N Engl J Med 2023 Jul 13;389(2):127-136 Background: Whether prehospital administration of tranexamic acid increases the likelihood of survival with a favorable functional outcome among patients with major trauma and suspected trauma-induced coagulopathy who are being treated in advanced trauma systems is uncertain. Methods: We randomly assigned adults with major […]

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Uncategorized Published - 19 October, 2023    By - Dr Clemens
Patient Well-being and Satisfaction after General or Local Anesthesia with Conscious Sedation: A Secondary Analysis of the SOLVE-TAVI Trial

Authors: Matthias Heringlake, M.D. et al Anesthesiology November 2023, Vol. 139, 701–704. To the Editor: Transfemoral transcatheter aortic valve replacement has become the standard of care for older patients with symptomatic aortic stenosis.  While most procedures were initially performed under general anesthesia, based on the assumption that avoiding general anesthesia may improve postinterventional well-being and patient satisfaction, […]

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Uncategorized Published - 19 October, 2023    By - Dr Clemens
Novel Pulsed Ultrahigh-frequency Spinal Cord Stimulation Inhibits Mechanical Hypersensitivity and Brain Neuronal Activity in Rats after Nerve Injury

Authors: Chin-Tsang Yang, Ph.D. et al  Anesthesiology November 2023, Vol. 139, 646–663. Background Spinal cord stimulation (SCS) is an important pain treatment modality. This study hypothesized that a novel pulsed ultrahigh-frequency spinal cord stimulation (pUHF-SCS) could safely and effectively inhibit spared nerve injury–induced neuropathic pain in rats. Methods Epidural pUHF-SCS (± 3V, 2-Hz pulses comprising 500-kHz […]

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