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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Pulmonary Hypertension

AUTHORS: Meng, Marie-Louise MD et al Anesthesia & Analgesia May 16, 2023. BACKGROUND: Patients with pulmonary hypertension have a high risk of maternal morbidity and mortality. It is unknown if a trial of labor carries a lower risk of morbidity in these patients compared to a planned cesarean delivery. The objective of this study was […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications

AUTHORS: Haller G et al European Journal of Anaesthesiology 34(8):p 492-507, August 2017.  BACKGROUND  Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these patients. OBJECTIVES To determine the incidence of surgical patients at increased risk of PPCs, and […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling

AUTHORS: Chen, Zhao-Rong MM et al  Anesthesia & Analgesia 137(2):p 426-439, August 2023. BACKGROUND: Myocardial infarction is a common perioperative complication, and blood flow restoration causes ischemia/reperfusion injury (IRI). Dexmedetomidine (DEX) pretreatment can protect against cardiac IRI, but the mechanism is still insufficiently understood. METHODS: In vivo, myocardial ischemia/reperfusion (30 minutes/120 minutes) was induced via ligation […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Project SPRUCE: Saving Our Planet by Reducing Carbon Emissions, a Pediatric Anesthesia Sustainability Quality Improvement Initiative

AUTHORS: Hansen, Elizabeth E. MD, PhD et al  Anesthesia & Analgesia 137(1):p 98-107, July 2023. BACKGROUND: Children are particularly vulnerable to adverse health outcomes related to climate change. Inhalational anesthetics are potent greenhouse gasses (GHGs) and contribute significantly to health care–generated emissions. Desflurane and nitrous oxide have very high global warming potentials. Eliminating their use, as […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Management of Muscle Relaxation With Rocuronium and Reversal With Neostigmine or Sugammadex Guided by Quantitative Neuromuscular Monitoring

AUTHORS: Thilen, Stephan R. MD, MS et al  Anesthesia & Analgesia May 12, 2023. BACKGROUND: The optimal pharmacological reversal strategy for neuromuscular blockade remains undefined even in the setting of strong recommendations for quantitative neuromuscular monitoring by several national and international anesthesiology societies. We evaluated a protocol for managing rocuronium blockade and reversal, using quantitative […]

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