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AUTHORS: Zhang, Zuoxia MD, PhD et al Anesthesia & Analgesia January 19, 2024. BACKGROUND: The microglial activation has been implicated in cancer-induced bone pain. Recent studies have revealed that microglia mediate synaptic pruning in the central nervous system, where the cluster of differentiation 47-signal regulatory protein α (CD47-SIRPα) axis creates a “don’t eat me” signal […]
Read MoreAUTHORS: Sotelo-Hitschfeld, Pamela PhD et al Anesthesia & Analgesia January 18, 2024. BACKGROUND: The trigeminal ganglion (TG) collects afferent sensory information from various tissues. Recent large-scale RNA sequencing of neurons of the TG and dorsal root ganglion has revealed a variety of functionally distinct neuronal subpopulations, but organ-specific information is lacking. METHODS: To link transcriptomic […]
Read MoreAuthor: Rebecca Pifer HealthcareDive Here’s what experts saw in their crystal balls for the coming year, including a spike in the uninsured rate and calmer waters in Medicare Advantage. The new year dawned on a health insurance industry beset by challenges. Only 7% of health plan executives view 2024 positively after being hammered by the coronavirus pandemic, […]
Read MoreAUTHORS: Morax, Laurent MD et al Anesthesia & Analgesia January 19, 2024. BACKGROUND: Subarachnoid hemorrhage (SAH) is associated with neurocognitive impairment. Recent data suggest that sevoflurane attenuates edema formation after SAH in rats. However, so far, no information is available about the long-term repair phase, nor if sevoflurane impacts functionality by increasing vascularity. This study […]
Read MoreAUTHORS: Brown, Sydney E.S. MD, PhD et al Anesthesia & Analgesia January 19, 2024. BACKGROUND: Sugammadex was initially approved for reversal of neuromuscular blockade in adults in the United States in 2015. Limited data suggest sugammadex is widely used in pediatric anesthesia practice however the factors influencing use are not known. We explore patient, surgical, […]
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