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Uncategorized Published - 8 May, 2024    By - Dr Clemens
Medicare hospital trust fund extended by 5 years to 2036

Author: Noah Tong Fierce Healthcare A new report finds the Medicare hospital trust fund will be solvent for 12 more years instead of seven. (Getty Images/ Andrii Yalanskyi) The Hospital Insurance Trust Fund will be fully solvent for longer than previously projected, according to an annual Medicare Trustee report. Though the report (PDF) details “significant financing issues,” […]

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Uncategorized Published - 7 May, 2024    By - Dr Clemens
Intrathecal Opioid Use in Kidney Transplantation

AUTHORS: Hofer, Ryan E. MD et al  Anesthesia & Analgesia October 06, 2023. BACKGROUND: Kidney transplant is the most common transplant operation performed in the United States. Although various approaches to pain management have been described, the optimal analgesic strategy remains undefined. Specifically, the role of intrathecal opioids in this patient population has not been […]

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Uncategorized Published - 7 May, 2024    By - Dr Clemens
Population Pharmacokinetics of Single Bolus Dose Fentanyl in Obese Children

AUTHORS: Okada, Carol R. MD et al  Anesthesia & Analgesia 138(1):p 99-107, January 2024. BACKGROUND: Childhood obesity is a significant problem. Obesity may alter the pharmacokinetics (PKs) of medications. Fentanyl is commonly used for procedural sedation, but there is a paucity of bolus dose fentanyl PK data in obese children. Better understanding of fentanyl PK in […]

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Uncategorized Published - 7 May, 2024    By - Dr Clemens
Balancing opioid medication in chronic pain

AUTHORS: L. JOSEPH PARKER, MD KevinMD.com She walked in with a cane, bent over like a question mark. She was in her seventies and as sweet as people in that age group tend to be. I think most of the cranky ones don’t make it that far. She was something of an emergency because her […]

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Uncategorized Published - 7 May, 2024    By - Dr Clemens
Influence of Intravenous S-Ketamine on the Pharmacokinetics of Oral Morphine in Healthy Volunteers

AUTHORS: Lohela, Terhi J. MD, PhD et al   Anesthesia & Analgesia 138(3):p 598-606, March 2024. BACKGROUND: Subanesthetic ketamine may reduce perioperative consumption of opioids. We studied whether intravenous S-ketamine alters the pharmacokinetics of oral morphine in healthy volunteers. METHODS: In this paired, randomized, double-blind, crossover trial, 12 participants under a 2-hour intravenous S-ketamine (0.57 mg/kg/h) […]

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