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Authors: Nikolai Ratajczak, cand. med et al Anesthesiology May 2024. Background Acetaminophen and 5-hydroxytryptamine-type-3 (5-HT3) receptor antagonists are administered as standard prophylaxes for postoperative pain, nausea, and vomiting. Preclinical studies however suggest that 5-HT3 antagonists may compromise acetaminophen’s analgesic effect. This hospital registry study investigates whether 5-HT3 antagonists mitigate the analgesic effect of prophylactic acetaminophen in a […]
Read MoreAuthors: Ian Yuan, MD, MEng. et al Anesthesiology May 2024. Background Unlike expired sevoflurane concentration, propofol lacks a biomarker for its brain effect site concentration (Ce), leading to dosing imprecision particularly in infants. Electroencephalography (EEG) monitoring can serve as a biomarker for propofol Ce, yet proprietary EEG indices are not validated in infants. We evaluated […]
Read MoreSomnia Anesthesia In the realm of healthcare reform, the American Society of Anesthesiologists has coined the concept of the “Three Rs” – delivering the right care, in the right place, at the right time. However, when it comes to anesthesia management, Somnia proposes expanding this framework to encompass two additional Rs: the right provider and […]
Read MoreAUTHORS: Blumberg, Neil MD et al Anesthesia & Analgesia 138(5):p 921-924, May 2024. Two recent commentaries,1 1 in the current issue of this journal,2 have addressed pressing issues concerning a commonly used therapy, platelet transfusion. Both are timely and succinct, pointing out that current practices are making life difficult for transfusion services, clinicians, and almost certainly harming patients. […]
Read MoreAuthor: Richard Novak, MD THE ANESTHESIA CONSULTANT Anesthesiologists work with surgeons of every specialty. Remarkable surgeons made world-changing breakthroughs during the past 70 years. The top 10 surgical advances during this time included: • THE HEART-LUNG MACHINE • ARTHROSCOPY • HEART TRANSPLANTATION • THE FIBEROPTIC ENDOSCOPE • VIDEOLAPAROSCOPY • INTERVENTIONAL RADIOLOGY/ANGIOPLASTY/STENTS • LIVER TRANSPLANTATION • […]
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