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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Antithrombin Deficiency during Venoarterial Extracorporeal Membrane Oxygenation: Extremely Common, but Does It Matter?

Authors: Michael Mazzeffi, M.D., M.P.H., F.A.H.A. et al  Anesthesiology June 2024, Vol. 140, 1065–1067. “Management strategies for anticoagulating adult ECMO patients and optimal management continue to be a work in progress.” In this issue of Anesthesiology, Mansour et al. explore the significance of antithrombin deficiency, defined by a time-weighted average antithrombin activity less than 70%, in adults […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Reversal for Respiratory Depression: Let’s Take a Breath!

Author: Thomas K. Henthorn, M.D. Anesthesiology June 2024, Vol. 140, 1059–1061. “Jansen et al. provide evidence that a new BK-channel blocker (i.e., ENA-001) […] may reverse the respiratory depressant effects of propofol, which may add to the utility of arousal-promoting agents and promises its own additional utility of ameliorating propofol’s respiratory depressant effects while permitting sedation.” Respiratory depression […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Addressing Postdural Puncture Headache: Guiding Clinicians Through Diagnosis and Management

Authors: Dibash Kumar Das, PhD; Pamela Flood, MD, MA ASA Monitor March 2024, Vol. 88, 1–4. Postdural puncture headache (PDPH) is a well-recognized complication resulting from a dural puncture during epidural analgesia, spinal anesthesia, or other neuraxial interventions. The incidence of unintended dural puncture during placement of an epidural catheter ranges widely, from less than 1% […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Improving Outcomes in Hip Fractures with Regional Anesthesia

Author: Kelly Wolfgang ASA Monitor April 2024, Vol. 88, 27. Emerging evidence suggests that patients who suffer hip fractures and other traumatic injuries are at risk of prolonged opioid use when inadequate analgesia occurs. For anesthesiologists, proper acute pain management is imperative, from preoperative patient assessment to the postoperative recovery stage. Uncontrolled pain can be detrimental, […]

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Uncategorized Published - 22 May, 2024    By - Dr Clemens
Influence of clinical and genetic factors on propofol dose requirements

Authors: Sirkku Ahlström, M.D. et al  Anesthesiology May 2024. Background Propofol is a widely used intravenous hypnotic. Dosing is mostly based on weight with great interindividual variation in consumption. Suggested factors affecting propofol requirements include age, gender, ethnicity, anxiety, alcohol consumption, smoking, and concomitant valproate use. Genetic factors have not been widely explored. Methods We […]

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