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Uncategorized Published - 22 October, 2025    By - Dr Clemens
Mixed-Methods Analysis of Preoperative Distress and Postoperative Outcomes in a Prospective, Observational Cohort of Older Adults

Authors: Kjaerulff I. et al. Anesthesiology, October 3, 2025. DOI: 10.1097/ALN.0000000000005780 This mixed-methods analysis explored how preoperative psychological distress influences postoperative outcomes in older surgical patients—a critical but underexamined aspect of perioperative care. Despite calls for routine distress screening in geriatric populations, evidence linking preoperative distress to clinical outcomes has been sparse. The study analyzed […]

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Uncategorized Published - 22 October, 2025    By - Dr Clemens
Intraoperative Cardiac Events in Pediatric Patients with Congenital Heart Disease Undergoing Noncardiac Procedures

Authors: Nasr V.G. et al. Anesthesiology, October 3, 2025. DOI: 10.1097/ALN.0000000000005783 This large multicenter registry analysis provides one of the most comprehensive assessments to date of intraoperative cardiac events in pediatric patients with congenital heart disease (CHD) undergoing noncardiac procedures. Prior research on this high-risk group has been limited by either national datasets lacking clinical […]

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Uncategorized Published - 22 October, 2025    By - Dr Clemens
Anesthesia’s ‘untapped resource’

Author: Francesca Mathewes Becker’s ASC Review ASCs are poised for growth over the next several years as CMS and payer policy, patient preference and demand for surgical services push more cases into the outpatient setting. While this potential for growth is promising for many ASCs, anesthesia coverage remains a core issue as the shortage of […]

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Uncategorized Published - 22 October, 2025    By - Dr Clemens
Efficacy and safety of preemptive magnesium sulfate infusion during pheochromocytoma and paraganglioma resection

Authors: Kong H. et al. Anesthesiology, October 3, 2025. DOI: 10.1097/ALN.0000000000005778 This randomized, double-blind clinical trial investigated whether preemptive magnesium sulfate infusion could improve intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—a surgery characterized by extreme fluctuations in blood pressure and heart rate due to catecholamine surges. Despite magnesium’s known sympatholytic and vasodilatory properties, […]

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Uncategorized Published - 22 October, 2025    By - Dr Clemens
General anesthesia and systemic hyperosmolality modulate lumbar intrathecal drug distribution in female rats

Authors: Persson N.D.Å. et al. Anesthesiology, October 9, 2025. DOI: 10.1097/ALN.0000000000005794 This preclinical study examined how anesthesia type and systemic osmotic state influence the central nervous system (CNS) distribution of drugs administered via the lumbar intrathecal route. While intrathecal drug delivery bypasses the blood-brain barrier, it often fails to achieve therapeutic concentrations in the brain, […]

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