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Authors: Duarte F F, Dias N M Cureus 16(8): e65940. Abstract Myelomeningocele (MMC) is an in-utero closure defect of the posterior portion of the neural tube, and it is the most common neural tube defect (NTD) compatible with life. It is usually associated with other congenital malformations, such as hydrocephalus and Chiari type 2 syndrome. […]
Read MoreAuthors: Mei Li, M.D. et al Anesthesiology July 2024. Background As a mechanosensitive cation channel and key regulator of vascular barrier function, endothelial transient receptor potential vanilloid-type 4 (TRPV4) contributes critically to ventilator-induced lung injury (VILI) and edema formation. Ca2+ influx via TRPV4 can activate Ca2+-activated K + (KCa) channels, categorized into small (SK1-3), intermediate (IK1), and big […]
Read MoreAuthors: Arun T, Karim H R, Singha S K, et al. Cureus 16(6): e63380. Background: In the search for opioid-free anesthesia, notable numbers of drugs, singly or in combinations, have been tested with variable results. However, most of the drugs used are not as strong as opioids. Even if some non-opioid drugs are potent enough, […]
Read MoreAuthors: Kaserer, Alexander MD, DESAIC et al Anesthesia & Analgesia 138(3):p 496-498, March 2024. Managing acute bleeding in the intensive care unit (ICU) remains a major challenge. Blood loss and also the transfusion of red blood cells (RBCs), plasma, and platelets are associated with adverse outcomes and high costs. A systematic approach guided by point-of-care testing […]
Read MoreAuthors: Lim Yiqi O, Au-Yong A Cureus 16(8): e65937. Abstract Anterior neck haematoma is a rare but potentially fatal emergency due to airway obstruction after a surgical intervention of the neck. Complete airway obstruction can be rapid and deteriorate exponentially. In a patient with a previously normal laryngeal view during his Sistrunk procedure, we describe […]
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