⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Uncategorized Published - 9 February, 2015    By - Dr Clemens
5 tips for future physician leaders

WRITTEN BY EDWARD R. MARIANO, MD Our health care system needs more physician leaders. Physician-led accountable care organizations have been shown to improve the quality of patient care while reducing overall costs. Physicians, by their nature, tend to be goal-oriented, have the ability to gather and assimilate evidence, and make difficult decisions, but these traits […]

Read More
Uncategorized Published - 6 February, 2015    By - Dr Clemens
Elevated Risk for Thrombotic Events After Superficial Venous Thrombosis

Published in  Blood 2015 Jan 8; 125:229 Authors: Cannegieter SC et al. Risks were higher for subsequent deep venous thrombosis, pulmonary embolism, acute myocardial infarction, ischemic stroke, and death. A recent study showed that 9.4% of patients with superficial venous thrombosis (SVT) had extension of the thrombus to the deep veins (NEJM JW Oncol Hematol Sep […]

Read More
Uncategorized Published - 6 February, 2015    By - Dr Clemens
Phase 1 Safety Assessment of Intrathecal Oxytocin

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 407-413. doi:10.1097/ALN.0000000000000539 Authors: James C. Eisenach, M.D et al Background: Preclinical data suggest that oxytocin reduces hypersensitivity by actions in the spinal cord, but whether it produces antinociception to acute stimuli is unclear. In this article, the authors examined the safety of intrathecal oxytocin […]

Read More
Uncategorized Published - 6 February, 2015    By - Dr Clemens
Effect of Minocycline on Lumbar Radicular Neuropathic Pain: A Randomized, Placebo-controlled, Double-blind Clinical Trial with Amitriptyline as a Comparator

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 399-406. doi:10.1097/ALN.0000000000000508 Authors: Pascal Vanelderen, M.D. et al Background: Less than 50% of patients experience sufficient pain relief with current drug therapy for neuropathic pain. Minocycline shows promising results in rodent models of neuropathic pain but was not studied in humans with regard to […]

Read More
Uncategorized Published - 6 February, 2015    By - Dr Clemens
Reversal of Dabigatran Effects in Models of Thrombin Generation and Hemostasis by Factor VIIa and Prothrombin Complex Concentrate

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 353-362. doi:10.1097/ALN.0000000000000540 Authors: Maureane Hoffman, M.D. et al Background: The oral thrombin inhibitor dabigatran has the drawbacks that it does not have a validated antidote. Data from animal studies and plasma coagulation assays suggest that prothrombin complex concentrate (PCC) or recombinant factor VIIa (FVIIa) […]

Read More