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Uncategorized Published - 23 July, 2015    By - Dr Clemens
Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis

Medicine (Baltimore) 2015 Apr;94(14):e597 Authors: Li B et al Abstract Many studies have reported the beneficial effects of dexmedetomidine on postoperative neurocognitive function but overall evidence is not as clear. We examined this conundrum by meta-analyzing studies that used dexmedetomidine in perioperative conditions or as intensive care unit (ICU) sedation and utilized reliable neurocognitive assessment tests. The […]

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Uncategorized Published - 23 July, 2015    By - Dr Clemens
FDA OKs First Patient-Controlled Patch for Postop Pain

The US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]

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Uncategorized Published - 22 July, 2015    By - Dr Clemens
Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection

World J Gastroenterol 2015 Mar 28;21(12):3671-8. Authors: Kim N et al AIM: To compare the efficacy and safety of sedation protocols for endoscopic submucosal dissection (ESD) between dexmedetomidine-remifentanil and propofol-remifentanil. METHODS: Fifty-nine patients scheduled for ESD were randomly allocated into a dexmedetomidine-remifentanil (DR) group or a propofol-remifentanil (PR) group. To control patient anxiety, dexmedetomidine or propofol was […]

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Uncategorized Published - 22 July, 2015    By - Dr Clemens
Impact of inhalation vs. intravenous anaesthesia on autonomic nerves and internal anal sphincter tone

Acta Anaesthesiol Scand 2015 Apr 21 Authors: Heid F et al BACKGROUND: Pelvic intraoperative neuromonitoring (pIONM) aims to identify and spare the autonomic nerves and maintain patients’ quality of life. The effect of anaesthetic agents on the pIONM signal is unknown; therefore, the aim of the present study was to compare the influences of inhalation anaesthesia (IA) […]

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Uncategorized Published - 22 July, 2015    By - Dr Clemens
The effect of two different doses of remifentanil on postoperative pain and opioid consumption after cardiac surgery – a randomized controlled trial

Acta Anaesthesiol Scand 2015 Apr 21. Authors: Florkiewicz P et al BACKGROUND: Remifentanil, an ultra-short-acting opioid, provides intensive analgesia without prolonged respiratory depression and is widely used in cardiac surgery. Diminished dosing may also offer stable hemodynamics, even during sternotomy and sternal retraction. However, increased postoperative pain and induced opioid tolerance after remifentanil dosing during abdominal surgery […]

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