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Uncategorized Published - 21 January, 2015    By - Dr Clemens
Sedation monitoring during open muscle biopsy in children by Comfort Score and Bispectral Index – a prospective analysis

Published in Paediatr Anaesth. 2014 Oct Authors: Tschiedel E et al BACKGROUND: Open muscle biopsies in children are generally performed under general anesthesia. Alternatively, deep sedation and analgesia may be required. OBJECTIVES: The aim of our study was to compare the Bispectral Index (BIS) and Comfort Score (CS) with respect to their clinical significance for […]

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Uncategorized Published - 21 January, 2015    By - Dr Clemens
Immune Response to Major GI Surgery, Blood Transfusions Mapped

Major gastrointestinal (GI) surgery promotes a specific gene expression pattern that upregulates the anti-inflammatory cytokine interleukin (IL)-10 while depressing proinflammatory immune pathways. Blood transfusions likely exacerbate this immune response, which also is associated with an increase in infectious complications. The finding raises the possibility that risk stratification for postoperative complications might use immunologic factors for […]

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Uncategorized Published - 20 January, 2015    By - Dr Clemens
Current Concepts In the Understanding of Malignant Hyperthermia

Tae W. Kim, MD Professor and Director of Quality Improvement Department of Anesthesiology University of Minnesota School of Medicine Staff Anesthesiologist University of Minnesota Children’s Hospital Minneapolis, Minnesota Henry Rosenberg, MD Director, Department of Medical Education and Clinical Research Saint Barnabas Medical Center Livingston, New Jersey President, Malignant Hyperthermia Association of the United States Sherburne, […]

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Uncategorized Published - 20 January, 2015    By - Dr Clemens
Sevoflurane anesthesia and brain perfusion

Published in Paediatr Anaesth. 2015 Feb;25(2):180-5 Authors: Rhondali O et al OBJECTIVE/AIM: To assess the impact of sevoflurane and anesthesia-induced hypotension on brain perfusion in children younger than 6 months. BACKGROUND: Safe lower limit of blood pressure during anesthesia in infant is unclear, and inadequate anesthesia can lead to hypotension, hypocapnia, and low cerebral perfusion. […]

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Uncategorized Published - 20 January, 2015    By - Dr Clemens
Pain in children – are we accomplishing the optimal pain treatment?

Published in Paediatr Anaesth. 2015 Jan;25(1):83-92 Author: Lundeberg S Abstract Morphine, paracetamol and local anesthetics have for a long time been the foremost used analgesics in the pediatric patient by tradition but not always enough effective and associated with side effects. The purpose with this article is to propose alternative approaches in pain management, not […]

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