⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Uncategorized Published - 26 March, 2015    By - Dr Clemens
FDA Declines Approval for Intranasal Migraine Treatment

The US Food and Drug Administration (FDA) has declined approval for a drug-device product combining low-dose sumatriptan powder delivered intranasally using a novel delivery technology for the treatment of migraine (AVP-825, Avanir Pharmaceuticals Inc), the company reports. “In the Complete Response letter (CRL), and consistent with the preliminary feedback announced on November 7, 2014, the […]

Read More
Uncategorized Published - 26 March, 2015    By - Dr Clemens
Persistent Postmastectomy Pain and Pain-Related Physical and Emotional Functioning With and Without a Continuous Paravertebral Nerve Block: A Prospective 1-Year Follow-Up Assessment of a Randomized, Triple-Masked, Placebo-Controlled Study

Published in Ann Surg Oncol. 2014 Nov 21. Authors: Ilfeld BM et al BACKGROUND: In a previous randomized, triple-masked, placebo-controlled study, the authors demonstrated that extending a single-injection paravertebral nerve block with a multiple-day perineural local anesthetic infusion improves analgesia and decreases pain-related dysfunction during the 3-day infusion but not subsequent to catheter removal within 1 month […]

Read More
Uncategorized Published - 26 March, 2015    By - Dr Clemens
Anesthetic management of patients with Joubert syndrome: a retrospective analysis of a single-institutional case series

Published in Paediatr Anaesth. 2014 Nov;24(11):1180-4. Authors: Sriganesh K et al OBJECTIVE: To analyze the anesthetic techniques used for sedation during magnetic resonance imaging (MRI) study of patients with Joubert syndrome (JS) and assess the safety and efficacy of these anesthetic regimens in these children. BACKGROUND: Joubert syndrome is a rare neurological disorder with significant anesthetic […]

Read More
Uncategorized Published - 26 March, 2015    By - Dr Clemens
Perioperative respiratory complications following awake and deep extubation in children undergoing adenotonsillectomy

Published in Paediatr Anaesth. 2015 Apr;25(4):392-9 Authors: Baijal RG et al BACKGROUND: Perioperative respiratory complications after adenotonsillectomy (T&A) are common and have been described to occur more frequently in children below 3 years of age, those with cranio-facial abnormalities, Down syndrome, obstructive sleep apnea, morbid obesity, and failure to thrive. AIMS: To investigate the association between awake […]

Read More
Uncategorized Published - 26 March, 2015    By - Dr Clemens
Unintentional epidural injection of 88 μg·kg(-1) of epinephrine

Published in Paediatr Anaesth. 2014 Nov;24(11):1185-7 Authors: August DA et al We report the effects of 88 μg·kg(-1) of epinephrine (1:10,000) injected into the caudal epidural space of a 42-week postconceptual age infant. No long-term neurological or cardiovascular sequelae occurred. Noninvasive cardiac output (CO) monitoring revealed increased CO, contractility, and stroke volume for about an hour, […]

Read More