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Uncategorized Published - 16 April, 2015    By - Dr Clemens
Palonosetron and Aprepitant for the Prevention of Postoperative Nausea and Vomiting in Patients Indicated for Laparoscopic Gynaecologic Surgery

Published in BMC Anesthesiol. 2014;14(68) Authors: Hyoung Yong Moon et al A Double-Blind Randomised Trial Abstract Background Postoperative nausea and vomiting (PONV) is one of the most common postsurgical complications. Palonosetron, a 5-hydroxytryptamine receptor antagonist, is effective for PONV prevention. Herein, we compared palonosetron and aprepitant (a neurokinin-1 receptor antagonist) for PONV prevention in patients […]

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Uncategorized Published - 16 April, 2015    By - Dr Clemens
Not Fit for a Haircut … How Should We Assess Fitness and Stratify Risk for Surgery?

Published in Br J Anaesth. 2014;112(6):955-957. Authors: M. A. Shulman, et al Owing to increases in life expectancy, the patients presenting for surgery are older, and have more co-morbidities. Worldwide, 3–4% of patients die within 2 months of major surgery, with increased mortality and morbidity in high-risk surgical candidates, including the elderly and medically unwell. In Australia […]

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Uncategorized Published - 16 April, 2015    By - Dr Clemens
Anaesthetic Drugs and Survival: A Bayesian Network Meta-analysis of Randomized Trials in Cardiac Surgery

Authors: G. Landoni, et al Published in Br J Anaesth. 2013;111(6):886-896. Background. Many studies have compared desflurane, isoflurane, sevoflurane, total i.v. anaesthesia (TIVA), or all in cardiac surgery to assess their effects on patient survival. Methods. We performed standard pairwise and Bayesian network meta-analyses; the latter allows indirect assessments if any of the anaesthetic agents were not compared […]

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Uncategorized Published - 16 April, 2015    By - Dr Clemens
Effects of Dexamethasone as a Local Anaesthetic Adjuvant for Brachial Plexus Block A Systematic Review and Meta-analysis of Randomized Trials

Published in Br J Anaesth. 2014;112(3):427-439. Authors: S. Choi, et al Background. Brachial plexus nerve blocks (BPBs) have analgesic and opioid sparing benefits for upper extremity surgery. Single-injection techniques are limited by the pharmacological duration and therapeutic index of local anaesthetics (LAs). Continuous catheter techniques, while effective can present management challenges. Off-label use of perineural dexamethasone as […]

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Uncategorized Published - 15 April, 2015    By - Dr Clemens
Gabapentin on Top of Regional Anaesthesia Helps Patients Undergoing Mastectomy Postoperatively

Multimodal perioperative analgesia with paravertebral nerve block (PVB) and gabapentin decreases the length of hospitalisation and narcotic usage in patients undergoing mastectomy compared to conventional postoperative management with on-demand postoperative medications (CPM), according to a study presented here at the 37th Annual San Antonio Breast Cancer Symposium (SABCS). The researchers say that the multimodality approach […]

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