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Uncategorized Published - 9 December, 2015    By - Dr Clemens
The Optimal Nerve Block for Knee Replacement Surgery

Discharge Readiness After Tricompartment Knee Arthroplasty: Adductor Canal Versus Femoral Continuous Nerve Blocks—A Dual-Center, Randomized Trial Authors: Machi AT, Sztain JF, Kormylo NJ, et al Anesthesiology. 2015;123:444-456 Study Summary This prospective randomized trial studied patients undergoing primary, unilateral knee arthroplasty to determine whether using a catheter to deliver a continuous adductor canal block reduced the interval […]

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Uncategorized Published - 8 December, 2015    By - Dr Clemens
Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer

Clin Ther. 2015 Nov 1;37(11):2468-75. Authors: Bista SR et al PURPOSE: Fentanyl is widely used to relieve cancer pain. However there is great interpatient variation in the dose required to relieve pain and little knowledge about the pharmacokinetic and pharmacodynamic (PK/PD) relationship of fentanyl and pain control. Patients with cancer are fragile and there is reluctance on […]

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Uncategorized Published - 8 December, 2015    By - Dr Clemens
Perioperative Duloxetine to Improve Postoperative Recovery After Abdominal Hysterectomy: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study

Anesthesia & Analgesia: September 2015 Authors: Castro-Alves, Lucas J. MD et al BACKGROUND: Postsurgical quality of recovery is worse in female than that in male patients. Duloxetine has been used successfully for the treatment of chronic pain conditions, but its use for preventing acute postoperative pain has been limited to a single previous study. More […]

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Uncategorized Published - 8 December, 2015    By - Dr Clemens
The Risk of Acute Kidney Injury from Fluid Restriction and Hydroxyethyl Starch in Thoracic Surgery

Anesthesia & Analgesia: September 2015 Authors: Ahn, Hyun Joo MD, PhD et BACKGROUND: Fluid is restricted in thoracic surgery to reduce acute lung injury, and hydroxyethyl starches (HES) are often administered to reduce fluid amount. This strategy may contribute to the development of acute kidney injury (AKI). We evaluated the incidence, risk factors, and prognosis […]

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Uncategorized Published - 8 December, 2015    By - Dr Clemens
Intraoperative Electroencephalogram Suppression Predicts Postoperative Delirium

Anesthesia & Analgesia: September 2015 Authors: Fritz, Bradley A. MD et al BACKGROUND: Postoperative delirium is a common complication associated with increased morbidity and mortality, longer hospital stays, and greater health care expenditures. Intraoperative electroencephalogram (EEG) slowing has been associated previously with postoperative delirium, but the relationship between intraoperative EEG suppression and postoperative delirium has […]

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