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Uncategorized Published - 29 April, 2015    By - Dr Clemens
Can remifentanil use in obstetrics be improved by optimal patient-controlled analgesia bolus timing?

Published in Br J Anaesth. 2015 Feb;114(2):281-9 Authors: Rehberg B et BACKGROUND: The safety of patient-controlled i.v. analgesia (PCA) with remifentanil for obstetrical analgesia remains a matter of concern. The efficacy of remifentanil bolus application, that is, the coincidence between pain and remifentanil effect-site concentration, may be improved by forecasting contractions, but it is not […]

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Uncategorized Published - 29 April, 2015    By - Dr Clemens
Feasibility of closed-loop co-administration of propofol and remifentanil guided by the bispectral index in obese patients: a prospective cohort comparison

Published in Br J Anaesth. 2015 Apr;114(4):605-14 Authors: Liu N et al BACKGROUND: We used an automated bispectral index (BIS)-guided dual-loop controller to determine propofol and remifentanil requirements during general anaesthesia in obese and lean surgical patients. METHODS: Obese patients, BMI>35 kg m(-2), and lean patients (<25 kg m(-2)) having laparoscopic procedures were prospectively evaluated […]

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Uncategorized Published - 29 April, 2015    By - Dr Clemens
Type of anaesthesia and patient quality of recovery: a randomized trial comparing propofol-remifentanil total i.v. anaesthesia with desflurane anaesthesia

Published in Br J Anaesth. 2015 Apr;114(4):663-8 Authors: Lee WK et al BACKGROUND: Two common general anaesthetic methods are total i.v. anaesthesia (TIVA) and inhalation anaesthesia, but it is unclear whether this affects the patient’s perception of their quality of recovery. The Quality of Recovery-40 questionnaire (QoR-40) is a valid and reliable method to evaluate […]

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Uncategorized Published - 29 April, 2015    By - Dr Clemens
Comparison of vestipitant with ondansetron for the treatment of breakthrough postoperative nausea and vomiting after failed prophylaxis with ondansetron

Published in Br J Anaesth. 2015 Mar;114(3):423-9 Authors: Kranke P et al BACKGROUND: Postoperative nausea and vomiting (PONV) is common; ondansetron is often used as prophylaxis or for breakthrough episodes. Vestipitant is a neurokinin 1 (NK-1) receptor antagonist that is effective for prophylaxis, but its efficacy for treating established PONV is unknown. This study was […]

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Uncategorized Published - 29 April, 2015    By - Dr Clemens
Effect of combining tramadol and morphine in adult surgical patients: a systematic review and meta-analysis of randomized trials

Published in Br J Anaesth. 2015 Mar;114(3):384-95 Authors: Martinez V et al The role for tramadol in multimodal postsurgical analgesic strategies remains unclear. We undertook a systematic review to evaluate the utility of combining tramadol with morphine after surgery. We searched the MEDLINE, EMBASE, LILAC, Cochrane, and Clinical Trial Register databases for randomized, controlled studies […]

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