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Uncategorized Published - 13 January, 2016    By - Dr Clemens
Impact of Metabolic Syndrome in Surgical Patients

Tzimas et al Br J Anaesth. 2015;115(2):194-202. Abstract Clinicians inevitably encounter patients who meet the diagnostic criteria for the metabolic syndrome (MetS); these criteria include central obesity, hypertension, atherogenic dyslipidaemia, and hyperglycaemia. Regardless of the variations in its definition, MetS may be associated with adverse outcomes in patients undergoing both cardiac and non-cardiac surgery. There is […]

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Uncategorized Published - 13 January, 2016    By - Dr Clemens
Epidural Blockade Affects the Pharmacokinetics of Propofol in Surgical Patients

Anesthesia & Analgesia: December 2015 Sitsen, Elske MD et al BACKGROUND: Neuraxial blockade reduces the dose requirements of sedative agents. It is unclear whether neuraxial blockade affects the pharmacokinetics and/or the pharmacodynamics of IV hypnotics. We therefore studied the influence of epidural blockade on the pharmacokinetics of propofol in patients scheduled for general surgery. METHODS: […]

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Uncategorized Published - 13 January, 2016    By - Dr Clemens
A Comparison of Photoplethysmography Versus Esophageal Doppler for the Assessment of Cardiac Index During Major Noncardiac Surgery

Anesthesia & Analgesia: December 2015 Blanié, Antonia MD et al BACKGROUND: In this prospective observational study, we compared changes in cardiac index (CI) during fluid challenge using photoplethysmography (PPG; Nexfin(TM)) (CIPPG) versus esophageal Doppler (ED) (CIED) in major noncardiac surgery patients. METHODS: Measurements were obtained when the attending anesthesiologist decided to perform a fluid challenge. […]

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Uncategorized Published - 13 January, 2016    By - Dr Clemens
Discordance in Grading Methods of Aortic Stenosis by Pre-Cardiopulmonary Bypass Transesophageal Echocardiography

Anesthesia & Analgesia: December 2015 Whitener, George MD et al BACKGROUND: Current guidelines define severe aortic valve stenosis (AS) as an aortic valve area (AVA) <=1.0 cm2 by the continuity equation and mean gradient ([DELTA]Pm) >= 40 mm Hg. However, these measurements can be discordant when classifying AS severity. Approximately one-third of patients with normal […]

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Uncategorized Published - 13 January, 2016    By - Dr Clemens
Risk for Cognitive Decline Greater in Older Women Following General Anesthesia and Surgery

Older women appear to be at higher risk than older men for deterioration in neurologic and cognitive functioning as well as ventricular brain volumes following the administration of general anesthesia and surgery. That was the conclusion of a study that tracked cognitive aging in more than 500 elderly people over time. Elderly women and men […]

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