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Uncategorized Published - 24 June, 2015    By - Dr Clemens
A Randomized, Double-blinded Trial of a “Rule of Threes” Algorithm versus Continuous Infusion of Oxytocin during Elective Cesarean Delivery

Published in Anesthesiology 7 2015, Vol.123, 92-100 Authors: Vesela P. Kovacheva, MD, PhD et al Background: The administration of uterotonic agents during cesarean delivery is highly variable. The authors hypothesized a “rule of threes” algorithm, featuring oxytocin 3 IU, timed uterine tone evaluations, and a systematic approach to alternative uterotonic agents, would reduce the oxytocin dose required […]

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Uncategorized Published - 24 June, 2015    By - Dr Clemens
Intraoperative Mean Arterial Pressure Variability and 30-day Mortality in Patients Having Noncardiac Surgery

Published in Anesthesiology 7 2015, Vol.123, 79-91. Authors: Edward J. Mascha PhD et al Background: Little is known about the relationship between intraoperative blood pressure variability and mortality after noncardiac surgery. Therefore, the authors tested the hypothesis that blood pressure variability, independent from absolute blood pressure, is associated with increased 30-day mortality. Methods: Baseline and intraoperative variables plus […]

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Uncategorized Published - 24 June, 2015    By - Dr Clemens
A Clinical Trial to Detect Subclinical Transfusion-induced Lung Injury during Surgery

Published in Anesthesiology 7 2015, Vol.123, 126-135. Authors: John R. Feiner, MD et al Background: Transfusion-related acute lung injury incidence remains the leading cause of posttransfusion mortality. The etiology may be related to leukocyte antibodies or biologically active compounds in transfused plasma, injuring susceptible recipient’s lungs. The authors have hypothesized that transfusion could have less severe effects […]

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Uncategorized Published - 23 June, 2015    By - Dr Clemens
Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study—Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

Published in Anesthesiology 7 2015, Vol.123, 38-54 Authors: Andrew J. Davidson, MD et al Background: Postoperative apnea is a complication in young infants. Awake regional anesthesia (RA) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designed to assess the influence of general […]

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Uncategorized Published - 23 June, 2015    By - Dr Clemens
Decision Aid for Cigarette Smokers Scheduled for Elective Surgery

Published in Anesthesiology 7 2015, Vol.123, 18-28 Authors: David O. Warner, MD et al Background: Decision aids can increase patient involvement in decision-making about health care. The study goal was to develop and test a decision aid for use by clinicians in discussion options for changing smoking behavior before and after elective surgery. Methods: In formative work, a […]

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