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Uncategorized Published - 28 July, 2015    By - Dr Clemens
Use of Aprepitant and Factors Associated With Incidence of Postoperative Nausea and Vomiting in Patients Undergoing Facial Plastic Surgery

Published in JAMA Facial Plast Surg, 2015 Jul 1;17(4):251-5. Authors: Trimas SJ et al IMPORTANCE: Patients who experience immediate postoperative nausea and vomiting (PONV) after their facial plastic surgery procedure have a higher incidence of complications and dissatisfaction. OBJECTIVES: To determine whether a single dose of aprepitant administered preoperatively can decrease the incidence of immediate PONV in […]

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Uncategorized Published - 28 July, 2015    By - Dr Clemens
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study

Published in BMJ, 2015 May 14;350:h2102. Authors: Desai RJ et al OBJECTIVE: To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk factors of history of opioid misuse or dependence, misuse of other substances, non-opioid […]

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Uncategorized Published - 27 July, 2015    By - Dr Clemens
Trash-Talking Anesthesiologist Hit With Judgment; More

The walls have ears, as the saying goes, but so do sedated patients whose smartphones have been set to “record.” In a recently concluded malpractice trial, that fact not only cost a Maryland doctor some money but subsequently her job, as a June 23 story in the Washington Post reports. The case involved a Vienna, Virginia, man […]

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Uncategorized Published - 27 July, 2015    By - Dr Clemens
Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer

Published in J Clin Anesth. 2015 May 30. pii: S0952-8180(15)00148-8 Authors: Linganna RE et al STUDY OBJECTIVE AND DESIGN: The mechanism of action of commonly used general anesthetics is largely unknown. One hypothesized mechanism is through modulation of microtubule stability. Taxanes, a subset of chemotherapeutic drugs known to alter microtubule stability and commonly used to treat breast […]

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Uncategorized Published - 27 July, 2015    By - Dr Clemens
Pain in the Frail or Elderly Patient: Does Tapentadol Have a Role?

Published in Drugs Aging. 2015 Jun;32(6):419-26. Authors: Veal FC et al Abstract Persistent pain affects the elderly disproportionally, occurring in 50 % of elderly community-dwelling patients and 80 % of aged care residents. The management of pain in the elderly and frail patient is complicated because of the risks posed by changes in pharmacokinetics and pharmacodynamics, polypharmacy, and drug-disease […]

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