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Anesthesia & Analgesia: September 2015 – Volume 121 – Issue 3 – p 652–660 Authors: Karan, Suzanne B. MD et al BACKGROUND: Physostigmine, a centrally acting acetylcholinesterase inhibitor, is most commonly used by anesthesiologists in the postanesthetic setting to reverse confusion caused by central anticholinergic medication effects. It has also been proposed as a treatment […]
Read MoreAnesthesia & Analgesia: September 2015 – Volume 121 – Issue 3 – p 645–651 Authors: Van Cleve et al BACKGROUND: The inverse relationship between age and dose requirement for potent volatile anesthetics is well established, but the question of whether anesthetic providers consider this relationship in practice remains unanswered. We sought to determine whether there […]
Read MoreAnesthesia & Analgesia: September 2015 – Volume 121 – Issue 3 – p 601–609 Authors: Tousignant, Claude MD, FRCPC et al Abstract Pulmonary hypertension and associated vascular changes may frequently accompany left-sided heart disease in the adult cardiac surgical population. Perioperative assessment of right ventricular function using echocardiography is well established. In general, understanding the […]
Read MorePain Med 2015 Aug Authors: Claroni C et al OBJECTIVE: Continuous surgical wound infusion with local anesthetics is an effective and widely used technique in postoperative pain management. Some aspects of this technique, however, require further investigation. The aim of this study was to retrospectively assess whether continuous infusion of ropivacaine delays the process of wound healing, […]
Read MorePain Med 2015 Aug Authors: Winegarden Jet al OBJECTIVE: We report a case of opioid-induced neurotoxicity (OIN) in an actively dying hospice patient, its reversal and improved analgesia that followed opioid dosage reduction made possible after addition of IV ketamine. We briefly review the diagnosis and treatment of OIN. SETTING: OIN, particularly when associated with high […]
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