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Uncategorized Published - 11 November, 2025    By - Dr Clemens
A Randomized Controlled Trial of Intraoperative Ketamine for Acute Postsurgical Pain after Breast Cancer Surgery

Authors: Wilson, Jenna et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005649 This prospective randomized controlled trial evaluated whether intraoperative ketamine reduces acute postsurgical pain in women undergoing breast cancer surgery, while also examining whether baseline temporal summation of pain (a measure of central sensitization) influences ketamine’s efficacy. A total of 225 patients were randomized to […]

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Uncategorized Published - 11 November, 2025    By - Dr Clemens
Effect of S-Ketamine on Postoperative Delirium in Elderly Patients Undergoing Arthroplasty

Authors: Zhu, Youzhuang et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005800 This randomized controlled trial evaluated whether S-ketamine can reduce postoperative delirium (POD) in elderly patients undergoing total hip or knee arthroplasty under neuraxial anesthesia. The study enrolled 372 patients between November 2023 and October 2024 at a high-volume arthroplasty center with standardized perioperative care […]

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Uncategorized Published - 11 November, 2025    By - Dr Clemens
Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC)

Authors: Shen, Fangming et al. Anesthesiology 2025 Oct 14 | DOI: 10.1097/ALN.0000000000005707 This multicenter randomized clinical trial (the AmPRAEC study) evaluated how different anesthesia-maintenance strategies affect postoperative respiratory adverse events (PRAEs) in children undergoing adenotonsillectomy. The investigators enrolled 760 children aged 0–12 years at 12 hospitals in China and randomly allocated them to one of […]

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Uncategorized Published - 11 November, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 10 November, 2025    By - Dr Clemens
Cognitive Decline and Dementia in Chronic Widespread Pain

Authors: Jiang, Xue et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005731 This large longitudinal cohort study investigated whether chronic widespread pain (CWP) contributes to cognitive decline and dementia, as well as potential underlying mechanisms involving brain structure and systemic inflammation. Using data from nearly 190,000 UK Biobank participants followed over 13 years, researchers examined self-reported […]

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