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Uncategorized Published - 28 October, 2015    By - Dr Clemens
Should We Restrict Erythrocyte Transfusion in Early Goal Directed Protocols?

Authors: Patrick Meybohm et al BMC Anesthesiol. 2015;15(75) Background: Early goal-directed therapy has been endorsed in the guidelines of the Surviving Sepsis Campaign as a key strategy among patients presenting with severe sepsis or septic shock. But more importantly, early goal-directed therapy also became standard care for non-septic critically ill patients and was adopted for high-risk surgical […]

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Uncategorized Published - 28 October, 2015    By - Dr Clemens
Safety and Efficacy of Combined Epidural/General Anesthesia During Major Abdominal Surgery in Patients With Increased Intracranial Pressure

Authors: Igor Zabolotskikh et al BMC Anesthesiol. 2015;15(76) Background: The increased intracranial pressure can significantly complicate the perioperative period in major abdominal surgery, increasing the risk of complications, the length of recovery from the surgery, worsening the outcome. Epidural anesthesia has become a routine component of abdominal surgery, but its use in patients with increased intracranial pressure […]

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Uncategorized Published - 27 October, 2015    By - Dr Clemens
CDC: Multiple Naloxone Doses May Be Needed for Fentanyl Overdoses

Multiple doses of naloxone may be needed to revive a patient after a fentanyl overdose, given fentanyl’s higher potency compared with other opioids, the CDC advised healthcare providers on Monday. In particular, nonpharmaceutical fentanyl — that is, illegally manufactured fentanyl and its analogs, often mixed with heroin or cocaine — tends to be especially potent. […]

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Uncategorized Published - 27 October, 2015    By - Dr Clemens
CDC Warning: Fentanyl-Related Fatalities, Seizures Rising

The Centers for Disease Control and Prevention (CDC) has issued an alert about increases in fentanyl drug confiscations and fentanyl-related overdose fatalities. Reports from the National Forensic Laboratory Information System, a program of the Drug Enforcement Administration’s (DEA’s) Office of Diversion Control, indicate a significant increase in the total number of fentanyl drug seizures reported […]

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Uncategorized Published - 27 October, 2015    By - Dr Clemens
Propofol: A Review of its Role in Pediatric Anesthesia and Sedation.

CNS Drugs, 2015 Jul;29(7):543-63. doi: 10.1007/s40263-015-0259-6. Authors: Chidambaran V et al Abstract Propofol is an intravenous agent used commonly for the induction and maintenance of anesthesia, procedural, and critical care sedation in children. The mechanisms of action on the central nervous system involve interactions at various neurotransmitter receptors, especially the gamma-aminobutyric acid A receptor. Approved for use […]

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