Authors:Emine Ozgur Bayman, PhD, et al Anesthesiology published on 11 2015. Background: One anesthesiologist performance metric is the incidence of “prolonged” (15 min or longer after dressing complete) times to extubation. The authors used several methods to identify the performance outliers and assess whether targeting these outliers for reduction could improve operating room workflow. Methods: Time to extubation data […]
Read MoreAuthors: Michael L. Beach, MD, PhD, et al Anesthesiology published on 11 2015. Background: Studies that have attempted to define the incidence of aspiration or pulmonary complications during sedation/anesthesia of children with respect to nil per os (NPO) status or other factors are difficult because of the relatively infrequent rate of these complications. Methods: The Pediatric Sedation Research Consortium consists of […]
Read MoreAuthors: Christian Jeleazcov MD. M.Sc, et al Anesthesiology published on 11 2015 Background: Patient-controlled analgesia (PCA) is a common method for postoperative pain therapy, but it is characterized by large variation of plasma concentrations. PCA with target-controlled infusion (TCI-PCA) may be an alternative. In a previous analysis, the authors developed a pharmacokinetic model for hydromorphone. In this secondary […]
Read MoreAuthors: Timothy J. Wigmore, MA, FRCA, FFCM, FFICM FCICM et al Anesthesiology published on 11 2015. Background: Surgical resection remains the best option for long-term survival in many solid tumors. Surgery can, however, lead to tumor cell release into the circulation. Data have suggested differential effects of anesthetic agents on cancer cell growth. This retrospective analysis investigated the […]
Read MoreThe FDA has approved a nasal spray version of naloxone hydrochloride (marketed as Narcan) to stop or reverse opioid overdose. The drug was previously approved only as an injection; the new version, says the agency, is both easier for first responders to administer and eliminates the risk for needlestick contamination. The drug is indicated for […]
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