⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Uncategorized Published - 3 December, 2015    By - Dr Clemens
Preemptive multimodal analgesia for postoperative pain management after lumbar fusion surgery: a randomized controlled trial.

Eur Spine J 2015 Sep 1. Authors: Kim SI MD et al PURPOSE: To assess the efficacy of a novel preemptive multimodal analgesic regimen for reducing postoperative pain and complications after primary lumbar fusion surgery. Preemptive multimodal analgesia is revealed to be an effective alternative to conventional morphine administration providing improved postoperative pain control with diminished side […]

Read More
Uncategorized Published - 3 December, 2015    By - Dr Clemens
Stochastic Pharmacokinetic–Pharmacodynamic Analysis of the Effect of Transdermal Buprenorphine on Electroencephalogram and Analgesia

Anesthesia & Analgesia: Nov 2015 Vol 121 Issue 5 p 1165-1175 Authors: Estrup Olesen, Anne PhD et al       BACKGROUND: The analgesic effect of opioids is often based on subjective one dimensional measurements. Electroencephalography (EEG) offers a possibility to objectively quantify the brain’s activity before and after the administration of opioids. The aim of this study […]

Read More
Uncategorized Published - 3 December, 2015    By - Dr Clemens
Oral Midodrine Hydrochloride for Prevention of Orthostatic Hypotension during Early Mobilization after Hip Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial

Authors: Olivind Jans, MD, PhD et al Anesthesiology 12 2015, Vol.123, 1292-1300. Background: Early postoperative mobilization is essential for rapid recovery but may be impaired by orthostatic intolerance (OI) and orthostatic hypotension (OH), which are highly prevalent after major surgery. Pathogenic mechanisms include an insufficient postoperative vasopressor response. The oral α-1 agonist midodrine hydrochloride increases vascular resistance, and […]

Read More
Uncategorized Published - 2 December, 2015    By - Dr Clemens
Perioperative Dextromethorphan as an Adjunct for Postoperative Pain: A Meta-analysis of Randomized Controlled Trials

Authors: Michael R. King, et al Anesthesiology published on 11 2015 Background: N-methyl-d-aspartate receptor antagonists have been shown to reduce perioperative pain and opioid use. The authors performed a meta-analysis to determine whether the use of perioperative dextromethorphan lowers opioid consumption or pain scores. Methods: PubMed, Web of Science, Cochrane Database of Systematic Reviews, Cochrane Central Register of […]

Read More
Uncategorized Published - 2 December, 2015    By - Dr Clemens
Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery

Authors: Miklos D. Kertai, MD, PhD et al Anesthesiology published on 11 2015 Background: Cardiac surgery requiring cardiopulmonary bypass is associated with platelet activation. Because platelets are increasingly recognized as important effectors of ischemia and end-organ inflammatory injury, the authors explored whether postoperative nadir platelet counts are associated with acute kidney injury (AKI) and mortality after coronary artery […]

Read More