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Uncategorized Published - 5 January, 2016    By - Dr Clemens
Preoperative use of platelets in a 6-year-old with acute appendicitis and a myosin heavy chain 9-related disorder: a case report and review of literature.

Transfusion 2015 Oct 7. doi: 10.1111/trf.13366. Authors: Eichel Y et al BACKGROUND: Mutations of nonmuscle myosin heavy chain 9 (MYH9) gene are an autosomal dominant cause of inherited thrombocytopenia in children. MYH9 spectrum disorders include May-Hegglin anomaly and Sebastian, Fechtner, and Epstein syndromes. Patients with these disorders often present with macroplatelets and thrombocytopenia and have a mild […]

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Uncategorized Published - 5 January, 2016    By - Dr Clemens
Steroid Injections May Ease Jaw Pain in JIA

Reviewed By: Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California San Francisco An intra-articular corticosteroid injection into the temporomandibular joint (TMJ) provides pain relief for some patients with juvenile idiopathic arthritis (JIA) whose orofacial symptoms haven’t responded to other pain management strategies. Note that the study identified considerable variation in terms of […]

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Uncategorized Published - 4 January, 2016    By - Dr Clemens
An Observational Study of Cerebral Blood Flow Velocity During Hypotensive Epidural Anesthesia

Anesthesia & Analgesia: Jan 2016 Vol 122 Issue 1 p226-233 Authors: Bombardieri, Anna Maria MD, PhD et al BACKGROUND: Hypotensive epidural anesthesia (HEA), as practiced at our institution, uses sympathetic blockade to achieve mean arterial blood pressure (MAP) of ≤50 mm Hg while administering epinephrine by infusion to support the circulation. HEA has not been associated […]

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Uncategorized Published - 4 January, 2016    By - Dr Clemens
Preoperative Acute Normovolemic Hemodilution for Minimizing Allogeneic Blood Transfusion: A Meta-Analysis

Anesthesia & Analgesia:Dec 2015 Volume 121 Issue 6 p1443-1455 Authors: Zhou, Xuelong MD et al BACKGROUND: Previous studies have evaluated the efficacy of preoperative acute normovolemic hemodilution (PANH) in reducing the need for allogeneic blood transfusion. However, the results to date have been controversial. In this study, we sought to reassess the efficacy and safety […]

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Uncategorized Published - 4 January, 2016    By - Dr Clemens
A Randomized Trial of a Supplemental Alarm for Critically Low Systolic Blood Pressure

Anesthesia & Analgesia: Dec 2045 Volume 121-Issue 6 p1500-1507 Authors: Panjasawatwong, Krit MD et al BACKGROUND: Intraoperative hypotension is associated with complications that might be ameliorated by earlier intervention. We therefore tested the primary hypothesis that a supplemental decision support alert for critically low systolic blood pressure (SBP) decreases the duration of intraoperative hypotension. METHODS: […]

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